Histopathological changes of sub chronic toxicity induced by oral administration of malathion in rock dove pigeons (Columba livia)‎

Abstract EN

The objective of the present study was to investigate the histopathological changes of the sub chronic toxicity of Malathion as organphosphorus insecticide in Rock dove pigeons ( Columba livia) treated orally with 6mg/kg and 4mg/kg body weight.

The histopathological changes of central and peripheral nervous systems , liver, kidney, skin of pigeon after three month of treatment were included, marked vacuolation of nerve fibers of spinal cord and sciatic nerve, periportal fibrosis and liver congestion ,degenerate renal cortical tubules ,associated with loss of epithelial lining and disorganization of epithelial lining , and cortical areas of inflammatory cells with congestion of blood vessels, and dermal fibrosis and inflammatory cells of the skin