Comparative study for some antioxidants in correction of oxidative stress markers for experimental induced diabetic rabbits
Other Title(s)
دراسة مقارنة لبعض مضادات الأكسدة في تصحيح معلمات الإجهاد التأكسدي للأرانب المصابة تجريبيا بداء السكري
Joint Authors
Abd, Afrah Jalil
Muhammad, Basimah Jasim
Aziz, Day Ali
Source
al-Qadisiyah Journal of Veterinary Medicine Sciences
Issue
Vol. 11, Issue 2 (31 Dec. 2012), pp.25-34, 10 p.
Publisher
al-Qadisiyah University College of Veterinary Medicine
Publication Date
2012-12-31
Country of Publication
Iraq
No. of Pages
10
Main Subjects
Abstract EN
Determination of reliable biochemical parameters of experimental diabetic rabbit by alloxane monohydrates and role of diatery antioxidants (ascorbic acid, vit.
A, and α-tocopherole) supplementation were investigated.
Body weight gain, blood (plasma) chemistries, antioxidant enzymes and histopathological lesion were determined over 10 week in new Zealand white rabbits: control T1 group, diabetic T2 group, diabetic and ascorbic acid T3 group, diabetic and Vit.
A T4 group, diabetic and α-tocopherole T5 animals group .
each of dietary ascorbic acid, vit.
A and α-tocopherole that given to animals of T3, T4 and T5 respectively were significantly (P≤0.01) reduced glucose level in blood than T2 diabetic group, also these antioxidants improve levels of cholesterol and triglyceride.
Enzymatic activity of liver glutathione peroxidase and superoxide dismutase were significantly increasd more than of diabetic animals T2.
histopathological structures of liver and pancrease confirm these results which indicate mild congestion and less degenerative signs in hepatocytes with mild degeneration of langerhans islets, generally oxidative stress resulted from diabetes and may diminished by administration of antioxidant ascorbic acid, Vit.
A and α-tocopherole supplementation, and α-tocopherole group was the best group.
American Psychological Association (APA)
Abd, Afrah Jalil& Muhammad, Basimah Jasim& Aziz, Day Ali. 2012. Comparative study for some antioxidants in correction of oxidative stress markers for experimental induced diabetic rabbits. al-Qadisiyah Journal of Veterinary Medicine Sciences،Vol. 11, no. 2, pp.25-34.
https://search.emarefa.net/detail/BIM-754834
Modern Language Association (MLA)
Abd, Afrah Jalil…[et al.]. Comparative study for some antioxidants in correction of oxidative stress markers for experimental induced diabetic rabbits. al-Qadisiyah Journal of Veterinary Medicine Sciences Vol. 11, no. 2 (2012), pp.25-34.
https://search.emarefa.net/detail/BIM-754834
American Medical Association (AMA)
Abd, Afrah Jalil& Muhammad, Basimah Jasim& Aziz, Day Ali. Comparative study for some antioxidants in correction of oxidative stress markers for experimental induced diabetic rabbits. al-Qadisiyah Journal of Veterinary Medicine Sciences. 2012. Vol. 11, no. 2, pp.25-34.
https://search.emarefa.net/detail/BIM-754834
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 31-33
Record ID
BIM-754834