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Effects of potassium and magnesium on some hematological profiles in two kidney, one clip-hypertensive and normotensive rats
Joint Authors
Mahmud, Almas M. R.
Uthman, Hawzin K.
Mawlud, Ismail Mustafa
Source
ZANCO Journal of Pure and Applied Sciences
Issue
Vol. 28, Issue 5 (31 Oct. 2016), pp.19-32, 14 p.
Publisher
Salahaddin University-Erbil Department of Scientific Publications
Publication Date
2016-10-31
Country of Publication
Iraq
No. of Pages
14
Main Subjects
Natural & Life Sciences (Multidisciplinary)
Abstract EN
In the current study the effects potassium and magnesium ions administration on blood parameters in 2-kidney one clip (2K1C) hypertensive and normotensive rats were investigated.
Seventy male albino rats were separated into two experiments.
The first experiment was performed to test the effects of potassium and magnesium on some haematological parameters included blood cell count, and platelet (PLT) indices in 2K1C hypertensive rats.
The second experiment was done on the normotensive rats measuring the same parameters in the first experiment.
The high blood pressure of 2K1C resulted in a significant elevation in RBCs, hemoglobin (HGB), WBCs count, granulocytes, monocytes and PLT count, while; statistical analysis showed a significant decrease in mean platelet volume (MPV) in 2K1C group.
Moreover, non-significant changes were observed in other blood parameters in 2K1C hypertensive rats.
Supplementation of potassium decreased RBCs count, hematocrit (HCT), WBCs count, granulocytes, monocytes and PLT count.
While it had non-significant effect in HGB, mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH), lymphocytes, MPV and PDW.
Magnesium alone and in combination with potassium caused not significant changes in RBCs, HGB, MCV, MCH, lymphocytes, MPV and MDW, while, significant decreases were recorded in granulocytes, monocytes and PLT in comparison to 2K1C rats.
In the second experiment, potassium alone and in combination with magnesium caused no significant differences in RBCs, HGB, HCT, MCV and MCH, wearers, RBCs, HGB and HCT were elevated by magnesium supplementation.
On the other hand, anon-significant changes were noticed MCV and MCH level in magnesium treated rat group.
Also, nonsignificant differences were recorded among the experimental groups in WBCs, granulocytes, lymphocytes, and monocytes, PLT, MPV and PDW.
Using magnesium and potassium ions supplementation alone or their combinations could improve the elevated WBCs, RBCs and PLTs counts in 2K1C hypertensive rats
American Psychological Association (APA)
Uthman, Hawzin K.& Mawlud, Ismail Mustafa& Mahmud, Almas M. R.. 2016. Effects of potassium and magnesium on some hematological profiles in two kidney, one clip-hypertensive and normotensive rats. ZANCO Journal of Pure and Applied Sciences،Vol. 28, no. 5, pp.19-32.
https://search.emarefa.net/detail/BIM-756710
Modern Language Association (MLA)
Uthman, Hawzin K.…[et al.]. Effects of potassium and magnesium on some hematological profiles in two kidney, one clip-hypertensive and normotensive rats. ZANCO Journal of Pure and Applied Sciences Vol. 28, no. 5 (2016), pp.19-32.
https://search.emarefa.net/detail/BIM-756710
American Medical Association (AMA)
Uthman, Hawzin K.& Mawlud, Ismail Mustafa& Mahmud, Almas M. R.. Effects of potassium and magnesium on some hematological profiles in two kidney, one clip-hypertensive and normotensive rats. ZANCO Journal of Pure and Applied Sciences. 2016. Vol. 28, no. 5, pp.19-32.
https://search.emarefa.net/detail/BIM-756710
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 31-32
Record ID
BIM-756710