Effect of green tea extract on injured liver induced by acetaaminophen in rabbits adult male
Other Title(s)
تأثير مستخلص الشاي الأخضر على التلف الكبدي المستحدث بالأست امينوفين في ذكور الأرانب البالغة
Author
Source
The Iraqi Journal of Agricultural Science
Issue
Vol. 47, Issue 6 (31 Dec. 2016), pp.1549-1555, 7 p.
Publisher
University of Baghdad College of Agriculture
Publication Date
2016-12-31
Country of Publication
Iraq
No. of Pages
7
Main Subjects
Topics
Abstract EN
Green tea is consider as a natural sources of antioxidants used to treat pathological changes occurring as a result of using of many drugs particularly in the liver tissue.
Forty adult male rabbits were randomly divided into four groups (10 rabbits /group) and were treated daily for 30 days as follows: first group (c): is the control group , second group (T1) : rabbits in this group were allowed to ad libitum supply of drinking water containing 2.5 gm /kg b.w of green tea extract , Third group (T2): rabbits in this group received 500 mg/kg b.w.
of acetaminophen orally, fourth group (T3) : rabbits in this group were allowed to ad libitum supply of drinking water containing 2.5 gm /kg b.w.
of green tea extract and received 500mg/kg b.w.
of Acetaminophen orally.
blood samples were collected for measuring the liver enzymes, cholesterol and triglyceride in blood serum at 15 and 30 days of experience.
The results of this study revealed that oral intubation of acetaminophen for 30 days caused hepatic dysfunction manifested by a significant elevation(P<0.05) in the serum AST,ALT ALP cholesterol and triglyceride while the animals received GTE with acetaminophen (T3) for 30 days showed a considerable decrease(P<0.05) in serum AST, ALT,ALP, cholesterol and triglyceride levels.
The histological section showed pathological changes in the liver tissue in (T2) group while giving green tea with acetaminophen was effective in modified these changes into semi normal
American Psychological Association (APA)
Mashi, Sawsan Kazim. 2016. Effect of green tea extract on injured liver induced by acetaaminophen in rabbits adult male. The Iraqi Journal of Agricultural Science،Vol. 47, no. 6, pp.1549-1555.
https://search.emarefa.net/detail/BIM-759292
Modern Language Association (MLA)
Mashi, Sawsan Kazim. Effect of green tea extract on injured liver induced by acetaaminophen in rabbits adult male. The Iraqi Journal of Agricultural Science Vol. 47, no. 6 (2016), pp.1549-1555.
https://search.emarefa.net/detail/BIM-759292
American Medical Association (AMA)
Mashi, Sawsan Kazim. Effect of green tea extract on injured liver induced by acetaaminophen in rabbits adult male. The Iraqi Journal of Agricultural Science. 2016. Vol. 47, no. 6, pp.1549-1555.
https://search.emarefa.net/detail/BIM-759292
Data Type
Journal Articles
Language
English
Notes
Text in English ; abstracts in English and Arabic.
Record ID
BIM-759292