Polymorphism study of MTHFR 677C→T and its correlation with oxidative stress and their influence on female infertility in Erbil-Iraq
Other Title(s)
دراسة متعددة الأشكال للجين MTHFR 677 C→T و ارتباطه مع الاجهاد التأكسدي و تأثيرهما على العقم عند النساء في محافظة أربيل-العراق
Joint Authors
al-Rawi, Khalid Faruq
Thabit, Muthanna Abd al-Ilah
Abd Allah, Kaylani Hikmat
Source
Issue
Vol. 14, Issue 3 (30 Sep. 2017), pp.611-618, 8 p.
Publisher
University of Baghdad College of Science for Women
Publication Date
2017-09-30
Country of Publication
Iraq
No. of Pages
8
Main Subjects
Topics
Abstract EN
This research includes a study of Methylenetetrahydrofolate reductase gene’s allele 677C→T and its correlation with oxidative stress and their impact on female infertility.
Fifty infertile women with the range age (23-42) years and twenty five fertile women with the range age (22-39) years as control group living in Erbil city were selected.
The serum level of Malondialdehyde (MDA), superoxide dismutase (SOD), prolactin hormone (PRL), Luteinizing hormone (LH), Thyroid stimulating hormone (TSH), Triiodothyronine hormone (T3), and Thyroxine hormone (T4) were measured, also a body mass index (BMI) was calculated.
A restriction enzyme (Hinf1) was used to improve the mutation in DNA bands of infertile women.
The results showed significant increases in MDA level, SOD activity, BMI, PRL, LH, TSH, and T4 in patients women compared with the control group.
The results show non-significant differences in T3 hormone levels.
The results also show a mutation in DNA bands of infertile women compared with fertile control group.-
American Psychological Association (APA)
Thabit, Muthanna Abd al-Ilah& Abd Allah, Kaylani Hikmat& al-Rawi, Khalid Faruq. 2017. Polymorphism study of MTHFR 677C→T and its correlation with oxidative stress and their influence on female infertility in Erbil-Iraq. Baghdad Science Journal،Vol. 14, no. 3, pp.611-618.
https://search.emarefa.net/detail/BIM-759930
Modern Language Association (MLA)
Thabit, Muthanna Abd al-Ilah…[et al.]. Polymorphism study of MTHFR 677C→T and its correlation with oxidative stress and their influence on female infertility in Erbil-Iraq. Baghdad Science Journal Vol. 14, no. 3 (2017), pp.611-618.
https://search.emarefa.net/detail/BIM-759930
American Medical Association (AMA)
Thabit, Muthanna Abd al-Ilah& Abd Allah, Kaylani Hikmat& al-Rawi, Khalid Faruq. Polymorphism study of MTHFR 677C→T and its correlation with oxidative stress and their influence on female infertility in Erbil-Iraq. Baghdad Science Journal. 2017. Vol. 14, no. 3, pp.611-618.
https://search.emarefa.net/detail/BIM-759930
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 616-617
Record ID
BIM-759930