![](/images/graphics-bg.png)
Gene frequencies of ABO and Rh blood groups in Nigeria : a review
Joint Authors
Anifowoshe, Abbas Toba
Owolodun, Olubukola Abibat
Akinseye, Kehinde Monica
Iyiola, Oluyinka Ajibola
Oyeyemi, Bolaji Fatai
Source
The Egyptian Journal of Medical Human Genetics
Issue
Vol. 18, Issue 3 (31 Jul. 2017), pp.205-210, 6 p.
Publisher
Egyptian Society of Human Genetics
Publication Date
2017-07-31
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Background: ABO and Rhesus factor (Rh) blood type are germane in human life in genetics and clinical studies.
Aim of the study: The review was undertaken with the objective to provide data on the ABO and Rh(D) blood group distribution and gene frequency across Nigeria which is vital for blood transfusion and susceptibility to disease.
Materials and methods: Literature search for ABO/Rh blood distribution in Nigeria was done and allele frequencies of A, B, O, D and d were calculated from the frequency recorded from six geopolitical zones in Nigeria.
We reported frequency of ABO and Rhesus blood type from 318,940 and 280,514 individuals respectively.
Prevalence were reported as percentage and Hardy-Weinberg equilibrium was tested using Chi square test and p was set at 0.05 unless otherwise stated.
Results: We reported ABO blood group frequencies in the order O > A > B > AB (52.93%, 22.77%, 20.64% and 3.66%) while prevalence of Rh+ was 94.90% from total population studied.
Our reported frequencies did not differ from Hardy-Weinberg equilibrium (goodness-of-fit X2 for ABO = 1.74 df = 3, p < 0.05).
Allelic frequencies for A(p), B(q) and O(r) are 0.143, 0.130 and 0.728 respectively.
Conclusion: The study provides information on the distribution/frequency of ABO/Rh(D) blood group and their corresponding allelic proportion in a large Nigeria study.
It also revealed how the Nigerian populations in the North, South, West and East vary with respect to genetic traits.
This vital information will be important for population genetics and anthropology studies and may be helpful in planning for future health strategy and blueprint, particularly planning with regards to disease management and blood transfusion medicine.
American Psychological Association (APA)
Anifowoshe, Abbas Toba& Owolodun, Olubukola Abibat& Akinseye, Kehinde Monica& Iyiola, Oluyinka Ajibola& Oyeyemi, Bolaji Fatai. 2017. Gene frequencies of ABO and Rh blood groups in Nigeria : a review. The Egyptian Journal of Medical Human Genetics،Vol. 18, no. 3, pp.205-210.
https://search.emarefa.net/detail/BIM-760002
Modern Language Association (MLA)
Oyeyemi, Bolaji Fatai…[et al.]. Gene frequencies of ABO and Rh blood groups in Nigeria : a review. The Egyptian Journal of Medical Human Genetics Vol. 18, no. 3 (Jul. 2017), pp.205-210.
https://search.emarefa.net/detail/BIM-760002
American Medical Association (AMA)
Anifowoshe, Abbas Toba& Owolodun, Olubukola Abibat& Akinseye, Kehinde Monica& Iyiola, Oluyinka Ajibola& Oyeyemi, Bolaji Fatai. Gene frequencies of ABO and Rh blood groups in Nigeria : a review. The Egyptian Journal of Medical Human Genetics. 2017. Vol. 18, no. 3, pp.205-210.
https://search.emarefa.net/detail/BIM-760002
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 209-210
Record ID
BIM-760002