Effect of salvia aegyptiaca aqueous extract on some neurohormonal disorders induced by carbon tetrachloride in adult male albino rats
Author
Source
Arab Journal of Nuclear Sciences and Applications
Issue
Vol. 50, Issue 3 (31 Jul. 2017), pp.205-216, 12 p.
Publisher
The Egyptian Society of Nuclear Science and Applications
Publication Date
2017-07-31
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Topics
Abstract EN
Daily intraperitoneal injection of carbon tetrachloride (CCl4) at a dose level of 1.0 ml/kg body weight caused a gradual and significant decrease in tyrosine amino acid.
As a result of this injection, dopamine (DA) and norepinephrine (NE) monoamines were decreased in different brain areas under investigation (cerebellum, pons & medulla oblongata, striatum, cerebral cortex, hypothalamus, midbrain, and hippocampus) where, CCl4 injection decreased serum luteinizing hormone (LH) and testosterone.
Animals that received a daily oral administration of Salvia aegyptiac aqueous extract at a dose equivalent to 2.0g/kg body weight, slightly increased brain contents of tyrosine, dopamine and norepinephrine.
Moreover a significant increase was observed in LH and testosterone from the first day till the end of the experiential period.
However, animals that were pretreated with a daily oral administration of Salvia aegeptiaca extract at a dose level equivalent to 2.0 g/kg body weight one hour before being intraperitoneally injected with CCl4, showed a significant increase in DA, NE, and tyrosine as compared to those treated with CCl4 alone; and thus Salvia extract may be attenuate CCl4 effect through experimental period
American Psychological Association (APA)
Abd al-Qadir, S. M.. 2017. Effect of salvia aegyptiaca aqueous extract on some neurohormonal disorders induced by carbon tetrachloride in adult male albino rats. Arab Journal of Nuclear Sciences and Applications،Vol. 50, no. 3, pp.205-216.
https://search.emarefa.net/detail/BIM-760064
Modern Language Association (MLA)
Abd al-Qadir, S. M.. Effect of salvia aegyptiaca aqueous extract on some neurohormonal disorders induced by carbon tetrachloride in adult male albino rats. Arab Journal of Nuclear Sciences and Applications Vol. 50, no. 3 (Jul. 2017), pp.205-216.
https://search.emarefa.net/detail/BIM-760064
American Medical Association (AMA)
Abd al-Qadir, S. M.. Effect of salvia aegyptiaca aqueous extract on some neurohormonal disorders induced by carbon tetrachloride in adult male albino rats. Arab Journal of Nuclear Sciences and Applications. 2017. Vol. 50, no. 3, pp.205-216.
https://search.emarefa.net/detail/BIM-760064
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 214-216
Record ID
BIM-760064