أهمية ارتفاع مستويات الشحوم الثلاثية في المصل في المراحل الباكرة من التهاب البنكرياس الصفراوي الحاد

Abstract EN

Objective : Pancreatitis induced by hypertriglyceridemia (HTG) has gained much attention.

However, very limited studies have focused on the clinical significance of TG elevation in non-HTG induced pancreatitis, such as acute biliary pancreatitis (ABP).

This study aimed to study the clinical significance of triglyceride (TG) elevation in patients with ABP.

Methods : We analyzed a total of 72 patients with acute biliary pancreatitis.

According to the highest TG level within 72 hours of disease onset, the patients were divided into a normal TG group (<150 mg/dl), and an elevated TG group (150 mg/dl or more).

We analyzed the differences between the two groups of patients in aspects such as general information, disease severity, revised Atlanta classification system, Ranson scores, complications and prognosis.

Results : Compared with the normal TG group, patients in the elevated TG group showed a significantly higher body mass index (BMI) and were older.

TG elevation at the early stage of acute biliary pancreatitis was associated with higher risk of severe pancreatitis and organ failures, especially respiratory failure.Conclusions: In acute biliary pancreatitis patients, TG elevation might participate in the aggravation of pancreatitis and the occurrence of systemic (but not local) complications.

Thus, the TG level may serve as an important indicator to determine the prognosis of patients with ABP.