Cytogenetical analysis in blood lymphocytes of cigarette smokers in Tiruchirappalli district, Tamil Nadu, India
Joint Authors
Christobher, S.
Periyasamy, M.
Muhammad, H. E. Sayyid
Bukhari, A. Sadiq
Karthickkumar, Alagamuthu
Balachandar, Vellingiri
Source
The Egyptian Journal of Medical Human Genetics
Issue
Vol. 18, Issue 2 (30 Apr. 2017), pp.148-152, 5 p.
Publisher
Egyptian Society of Human Genetics
Publication Date
2017-04-30
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Background: Tobacco smoke causes serious health ill effects to human population.
Cancer and cardiovascular diseases are more common in smoking subjects.
Aim: The present study is focused about the genetical changes in smoking subjects based on their age and pack years.
Subjects and methods: Based on a survey report, 160 subjects are selected from Tiruchirappalli district, Tamil Nadu, India.
Venous blood and buccal smear samples are collected from each subject.
Results: Increased CA is observed in heavy smokers compared to light and non smokers which is 8.90 ± 2.58, 4.58 ± 2.36 and 4.31 ±1.17, respectively.
Both medium and light smokers showed significantly increased CA frequencies than control.
Comet assay showed increased percentage of abnormalities in smokers (light, medium and heavy) than non-smokers.
Conclusion: The frequencies of MN in buccal epithelial and blood lymphocytes are high in smokers; particularly heavy smoker group showed significantly increased results.
Among them, the lymphocytic cells showed high MN frequency.
American Psychological Association (APA)
Christobher, S.& Periyasamy, M.& Muhammad, H. E. Sayyid& Bukhari, A. Sadiq& Karthickkumar, Alagamuthu& Balachandar, Vellingiri. 2017. Cytogenetical analysis in blood lymphocytes of cigarette smokers in Tiruchirappalli district, Tamil Nadu, India. The Egyptian Journal of Medical Human Genetics،Vol. 18, no. 2, pp.148-152.
https://search.emarefa.net/detail/BIM-760943
Modern Language Association (MLA)
Christobher, S.…[et al.]. Cytogenetical analysis in blood lymphocytes of cigarette smokers in Tiruchirappalli district, Tamil Nadu, India. The Egyptian Journal of Medical Human Genetics Vol. 18, no. 2 (Apr. 2017), pp.148-152.
https://search.emarefa.net/detail/BIM-760943
American Medical Association (AMA)
Christobher, S.& Periyasamy, M.& Muhammad, H. E. Sayyid& Bukhari, A. Sadiq& Karthickkumar, Alagamuthu& Balachandar, Vellingiri. Cytogenetical analysis in blood lymphocytes of cigarette smokers in Tiruchirappalli district, Tamil Nadu, India. The Egyptian Journal of Medical Human Genetics. 2017. Vol. 18, no. 2, pp.148-152.
https://search.emarefa.net/detail/BIM-760943
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 151-152
Record ID
BIM-760943