The clinico-epidemiologic characteristics of Iraqi patients with neuroendocrine tumors and their response to long acting octreotide
Joint Authors
al-Naqqash, Minwar A. Muhammad
Abd al-Fattah, Marwah K.
Source
Journal of the Faculty of Medicine Baghdad
Issue
Vol. 58, Issue 4 (31 Dec. 2016), pp.312-315, 4 p.
Publisher
University of Baghdad Faculty of Medicine
Publication Date
2016-12-31
Country of Publication
Iraq
No. of Pages
4
Main Subjects
Abstract EN
Background: The lack of studies regarding the neuroendocrine tumors (NET) is related to the rarity of these tumors .Long acting Octreotide is an established treatment for NETs by both providing symptomatic relief & inhibiting tumor growth.
However, studies regarding incidence of NETs & their response to long acting Octreotide are still insufficient.
Objectives: To study the clinico-pathologic characteristics of Iraqi patients with NET & their response to long acting Octreotide.
Patients & methods: This is a cross-sectional observational study that was conducted in Oncology teaching hospital using patients’ follow-up records.
Data recruitment included all NET patients diagnosed after October 2013.
Results: During the study period (2 years) ,38 patients were recorded in Iraq/oncology teaching hospital NET Registry.
Patients ` data (age, gender, site of the tumor, metastatic status as well as type of therapy applied) were collected.
Twenty one (55.3 %)of the patients were males, M:F=1.2:1 , while 23 patients (60.5%) were over the age of 50 years .The gastroenteropancreatic (GEP) tract being the most common primary site followed by pelvis We found metastatic disease at presentation in 17 (44.7% ) of patients and the Liver was the most common metastatic site found in (15.8%, 6 patients).
Seventeen (44.7%) patients presented with Grade 3 .
Most common therapy applied in our patients included systemic chemotherapy, surgery, long acting Sandostatin & radiotherapy for palliation only according to both NCCN & ESMO guidelines.
The median time of remission following Somatostatin analogue (SSA) administration was 3 months compared to 7 months in patients received other modalities of treatment (p=0.003).
Conclusion: Octreotide LAR provides symptomatic response & contributes to disease stabilization & tumor regression in both functional & non functional NETs.
American Psychological Association (APA)
Abd al-Fattah, Marwah K.& al-Naqqash, Minwar A. Muhammad. 2016. The clinico-epidemiologic characteristics of Iraqi patients with neuroendocrine tumors and their response to long acting octreotide. Journal of the Faculty of Medicine Baghdad،Vol. 58, no. 4, pp.312-315.
https://search.emarefa.net/detail/BIM-761042
Modern Language Association (MLA)
Abd al-Fattah, Marwah K.& al-Naqqash, Minwar A. Muhammad. The clinico-epidemiologic characteristics of Iraqi patients with neuroendocrine tumors and their response to long acting octreotide. Journal of the Faculty of Medicine Baghdad Vol. 58, no. 4 (2016), pp.312-315.
https://search.emarefa.net/detail/BIM-761042
American Medical Association (AMA)
Abd al-Fattah, Marwah K.& al-Naqqash, Minwar A. Muhammad. The clinico-epidemiologic characteristics of Iraqi patients with neuroendocrine tumors and their response to long acting octreotide. Journal of the Faculty of Medicine Baghdad. 2016. Vol. 58, no. 4, pp.312-315.
https://search.emarefa.net/detail/BIM-761042
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 315
Record ID
BIM-761042