Transcatheter aortic valve implantation : acute and 6-month outcomes of the first Lebanese experience and aliterature review

Abstract EN

Background : Transcatheter aortic valve implantation (TAVI) has recently emerged as a therapeutic alternative for high-risk surgical patients with severe symptomatic aortic valve stenosis and has been shown to improve clinical outcomes and reduce all-cause mortality in the PARTNER Trial.

However, there is still no published data on similar outcomes in the Lebanon.

Objectives : The aim of the study is to evaluate the immediate and short-term results of transfemoral (TF) and transaortic (TAo) TAVI done in Lebanon with 6 months follow-up.

Methods: From July 2012 till March 2015, 10 consecutive high-risk and intermediate risk patients with severe symptomatic AS underwent TAVI using Edwards SAPIEN valve.

The mean age was 79.4 ± 6.9 years, logistic EuroSCORE 12.56 ± 11.78 and mean STS 5.71 ± 2.44.

Patients were equally distributed among genders (50%).

The mean ejection fraction (EF) was 50.0 ± 14.9% and mean AV area 0.61 ± 0.1 cm2; mean aortic valve gradient (mAVG) 45.6 ± 20.2 mmHg, and AV annulus size 21.8 ± 1.8 mm.

Results: TF approach was performed in 9 patients (90%) and TAo in 1 patient (10%).

All valves (17 size 26 mm and 25 size 23 mm) were implanted successfully.

The overall 6-month survival was 80%.

Grade I paravalvular aortic regurgitation (AR) was present in 60% of the patients; grade II in 10% while none of the patients developed AR with grade III or VI.

The post-procedural mean aortic valve gradient (mAVG) was 9.77 ± 3.31 mmHg; EF was 52.5 ± 11.9% and immediate postoperative complications included only one case of newonset arrhythmia (AV Block).

After 6 months, one patient died of cardiac arrest following a massive pulmonary embolism while another patient died from a fatal stroke following infective endocarditis affecting the valve prosthesis.

Conclusion : TAVI is a feasible technique for intermediate/high risk AS with high success rate and acceptable complications.-