A study on strategies applied for enhancing anthraquinones production by Fusarium spp.

Abstract EN

Sixty Fusarium isolates were selected from different isolation sources and screened for their ability to produce anthraquinones; seventeen of which showed high or a moderate ability to produce anthraquinones.

Selected Fusarium isolates were screened for Fusaric acid production to exclude toxin-synthesis isolates.

F.

arthosporoides and F.

verticellioides showed the highest anthraquinones production since their production yields were 649.1 and 275.7 μg/g; respectively.

The anthraquinones derivatives produced by selected Fusarium strains were characterized by HPLC and GC-MS.

The optimization of fermentation conditions for F.

arthosporoides revealed that the maximum anthraquinones titer was achieved at 10 days of incubation period, pH 6.5 and 30°C and under shaking and light conditions.

For F.

verticellioides, the highest anthraquinones yield was accomplished after the same incubation period at pH 6.0, 25°C and under static and dark conditions.

Results evaluated the positive effect of ionizing (gamma) and non-ionizing (UV) irradiations on the anthraquinones production by F.

verticellioides since 0.25 kGy and 50 J/m2 enhanced the anthraquinone yield by nearly 30%.

The antimicrobial and dyeing properties of the produced anthraquinone are also studied.

The present study succeeded to reduce the cost of anthraquinones production by using kitchen garbage.