Patterns of phenotypic and genotypic resistance to macrolides, lincosamides and streptogramins group of antibiotics by efflux pump and enzymatic modification in methicillin resistant staphylococcus aureus
Other Title(s)
الأنماط المظهرية و الوراثية المقاومة لمجموعة مضادات الماكروليدات و اللنكوسأمايد و الستربتوغرامين في بكتريا Staphylococcus aureus المقاومة للمثيسيلين بألية الضخ خارج الخلية و التحوير الانزيمي
Joint Authors
Fulayyih, Mayy Talib
Muhammad, Lama Said
Source
Issue
Vol. 58, Issue 2B (30 Jun. 2017), pp.803-814, 12 p.
Publisher
University of Baghdad College of Science
Publication Date
2017-06-30
Country of Publication
Iraq
No. of Pages
12
Main Subjects
Abstract EN
The study was carried out to isolate Staphylococcus aureus isolates from differents clinical samples to detect resistance of isolates to methicillin and detect the phenotypic and genotypic patterns of resistance to macrolides, lincosamides and streptogramins (MLS).
The results showed that from 300 clinical sample there were 40 isolate related to S.aureus and there were 38(95)% of isolates were methicillin resistance S.aureus (MRSA).
The suscepltibility test showed that there was 55% of isolates were resistance to erythromycin , 35% were resistance to clindamycin and 2.5% had intermediate resistance to the last one .
The resistance to streptogramins determined phenotypicallyby the using of vitek 2 compact system,the results showed that there were four types of MLS resistance (iMLS, cMLS, M phenotype and SAB).
All isolates were subjected to polymerase chain reaction teqnique in a monoplex pattern to amplify resistance encoding genes msrA, msrB,linA/linA’ and vga .The results showed that 36(90)% of isolates contain msrA(940bp) and msrB(595bp) , 30 (75)% of isolates contain linA/linA’ (323bp) gene while a region of (470bp) of vga gene was not found in any isolate.
American Psychological Association (APA)
Muhammad, Lama Said& Fulayyih, Mayy Talib. 2017. Patterns of phenotypic and genotypic resistance to macrolides, lincosamides and streptogramins group of antibiotics by efflux pump and enzymatic modification in methicillin resistant staphylococcus aureus. Iraqi Journal of Science،Vol. 58, no. 2B, pp.803-814.
https://search.emarefa.net/detail/BIM-761260
Modern Language Association (MLA)
Muhammad, Lama Said& Fulayyih, Mayy Talib. Patterns of phenotypic and genotypic resistance to macrolides, lincosamides and streptogramins group of antibiotics by efflux pump and enzymatic modification in methicillin resistant staphylococcus aureus. Iraqi Journal of Science Vol. 58, no. 2B (2017), pp.803-814.
https://search.emarefa.net/detail/BIM-761260
American Medical Association (AMA)
Muhammad, Lama Said& Fulayyih, Mayy Talib. Patterns of phenotypic and genotypic resistance to macrolides, lincosamides and streptogramins group of antibiotics by efflux pump and enzymatic modification in methicillin resistant staphylococcus aureus. Iraqi Journal of Science. 2017. Vol. 58, no. 2B, pp.803-814.
https://search.emarefa.net/detail/BIM-761260
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 812-814
Record ID
BIM-761260