Immunohistochemical expression of membrane protein palmitoylated 6 (MPP6)‎ in mice testis

Abstract EN

Spermatogenesis is a process by which sperms are produced through successive mitosis of spermatogonia, meiosis of spermatocytes and maturation of spermatids.MPP6 mRNA was abundant in testis, brain, and kidney with lower levels detectable in other tissues.in the present study,the cellular localization of MPP6 in the mouse testis was analyzedbyenzyme histochemistry and immunofluorescence staining using polyclonal anti-rat antibody and paraffin tissue sections of mice testes.The histochemicalstaining revealed that the MPP6 waslocalized in the cytoplasm of elongated spermatid near to the lumen of seminiferous tubules while not expressed in other spermatogenic cells or in Sertoli cells.The expression of MPP6 in the elongated spermatids refers to the role of it at the level of spermiogenesis and suggest important role during maturation of elongated spermatids