Peripheral arterial stiffness is associated with higher baseline plasma uric acid : a prospective cohort study
Joint Authors
Zhang, Yun
Yang, Xu
Cao, Ruihua
Ye, Ping
Ding, Xiaohan
Xiao, Wenkai
Wu, Hongmei
Bai, Yongyi
Wang, Xiaona
Source
Saudi Journal of Biological Sciences
Issue
Vol. 24, Issue 3 (31 Mar. 2017), pp.574-581, 8 p.
Publisher
Publication Date
2017-03-31
Country of Publication
Saudi Arabia
No. of Pages
8
Main Subjects
Topics
Abstract EN
This prospective cohort study aimed at identifying association between uric acid (UA) and peripheral arterial stiffness.
A prospective cohort longitudinal study was performed according to an average of 4.8 years’ follow-up.
The demographic data, anthropometric parameters, peripheral arterial stiffness (carotid-radial pulse-wave velocity, cr-PWV) and biomarker variables including UA were examined at both baseline and follow-up.
Pearson’s correlations were used to identify the associations between UA and peripheral arterial stiffness.
Further logistic regressions were employed to determine the associations between UA and arterial stiffness.
At the end of followup, 1447 subjects were included in the analyses.
At baseline, cr-PWV (r = 0.200, p <0.001) was closely associated with UA.
Furthermore, the follow-up cr-PWV (r = 0.145, p< 0.001) was also strongly correlated to baseline UA in Pearson’s correlation analysis.
Multiple regressions also indicated the association between follow-up cr-PWV (b =0.493, p= 0.013) and baseline UA level.
Logistic regressions revealed that higher baseline UA level was an independent predictor of arterial stiffness severity assessed by cr-PWV at follow-up cross-section.
Peripheral arterial stiffness is closely associated with higher baseline UA level.
Furthermore, a higher baseline UA level is an independent risk factor and predictor for peripheral arterial stiffness.
American Psychological Association (APA)
Ding, Xiaohan& Ye, Ping& Wang, Xiaona& Cao, Ruihua& Yang, Xu& Xiao, Wenkai…[et al.]. 2017. Peripheral arterial stiffness is associated with higher baseline plasma uric acid : a prospective cohort study. Saudi Journal of Biological Sciences،Vol. 24, no. 3, pp.574-581.
https://search.emarefa.net/detail/BIM-761767
Modern Language Association (MLA)
Ding, Xiaohan…[et al.]. Peripheral arterial stiffness is associated with higher baseline plasma uric acid : a prospective cohort study. Saudi Journal of Biological Sciences Vol. 24, no. 3 (Mar. 2017), pp.574-581.
https://search.emarefa.net/detail/BIM-761767
American Medical Association (AMA)
Ding, Xiaohan& Ye, Ping& Wang, Xiaona& Cao, Ruihua& Yang, Xu& Xiao, Wenkai…[et al.]. Peripheral arterial stiffness is associated with higher baseline plasma uric acid : a prospective cohort study. Saudi Journal of Biological Sciences. 2017. Vol. 24, no. 3, pp.574-581.
https://search.emarefa.net/detail/BIM-761767
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 580-581
Record ID
BIM-761767