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Effect of aerobic exercise intervention on DDT degradation and oxidative stress in rats
Joint Authors
Zhu, Xiaohua
Wang, Yuzhan
Zheng, Shuqian
Dong, Guijun
Li, Kefeng
Source
Saudi Journal of Biological Sciences
Issue
Vol. 24, Issue 3 (31 Mar. 2017), pp.664-671, 8 p.
Publisher
Publication Date
2017-03-31
Country of Publication
Saudi Arabia
No. of Pages
8
Main Subjects
Topics
Abstract EN
Dichlorodiphenyltrichloroethane (DDT) reportedly causes extensively acute or chronic effects to human health.
Exercise can generate positive stress.
We evaluated the effect of aerobic exercise on DDT degradation and oxidative stress.
Main methods: Male Wistar rats were randomly assigned into control (C), DDT without exercise training (D), and DDT plus exercise training (DE) groups.
The rats were treated as follows: DDT exposure to D and DE groups at the first 2 weeks; aerobic exercise treatment only to the DE group from the 1st day until the rats are killed.
DDT levels in excrements, muscle, liver, serum, and hearts were analyzed.
Superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GSH-Px), and malondialdehyde (MDA) levels were determined.
Aerobic exercise accelerated the degradation of DDT primarily to DDE due to better oxygen availability and aerobic condition and promoted the degradation of DDT.
Cumulative oxidative damage of DDT and exercise led to significant decrease of SOD level.
Exercise resulted in consistent increase in SOD activity.
Aerobic exercise enhanced activities of CAT and GSH-Px and promoted MDA scavenging.
Results suggested that exercise can accelerate adaptive responses to oxidative stress and activate antioxidant enzymes activities.
Exercise can also facilitate the reduction of DDT-induced oxidative damage and promoted DDT degradation.
This study strongly implicated the positive effect of exercise training on DDT-induced liver oxidative stress.
American Psychological Association (APA)
Li, Kefeng& Zhu, Xiaohua& Wang, Yuzhan& Zheng, Shuqian& Dong, Guijun. 2017. Effect of aerobic exercise intervention on DDT degradation and oxidative stress in rats. Saudi Journal of Biological Sciences،Vol. 24, no. 3, pp.664-671.
https://search.emarefa.net/detail/BIM-761780
Modern Language Association (MLA)
Li, Kefeng…[et al.]. Effect of aerobic exercise intervention on DDT degradation and oxidative stress in rats. Saudi Journal of Biological Sciences Vol. 24, no. 3 (Mar. 2017), pp.664-671.
https://search.emarefa.net/detail/BIM-761780
American Medical Association (AMA)
Li, Kefeng& Zhu, Xiaohua& Wang, Yuzhan& Zheng, Shuqian& Dong, Guijun. Effect of aerobic exercise intervention on DDT degradation and oxidative stress in rats. Saudi Journal of Biological Sciences. 2017. Vol. 24, no. 3, pp.664-671.
https://search.emarefa.net/detail/BIM-761780
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 670-671
Record ID
BIM-761780