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Dynamic renal scintigraphic estimation of deceased donor kidneys in a rat model
Joint Authors
Mitil, Husayn Aydin
Koc, Zehra Pınar
Guzel, Yunus
Kom, Mustafa
Ozer, A. Belin
Ozercan, I. Hanefi
Balci, Tansel Ansal
Source
Saudi Journal of Kidney Diseases and Transplantation
Issue
Vol. 28, Issue 2 (30 Apr. 2017), pp.273-278, 6 p.
Publisher
Saudi Center for Organ Transplantation
Publication Date
2017-04-30
Country of Publication
Saudi Arabia
No. of Pages
6
Main Subjects
Topics
Abstract EN
At present a large number of the renal transplantations are being performed from the deceased donors.
The success of these transplantations depends on the viability of the deceased donor kidneys.
The aim of this study was to investigate the reliability of scintigraphic estimation of function of deceased donor kidneys by comparing the histopathologic and scintigraphic findings.
Ten rats were included in the study (2–3 months old, 250–300 g, all male).
Control scintigraphy was performed to all the rats by injection of 37 MBq Tc-99m DTPA from the tail vein in a dynamic manner.
Brain death of the rats was achieved by inflation of a Fogartys catheter in the cranial cavity.
Immediately, after brain death confirmation, dynamic renal scintigraphy was performed with the same parameters of control scintigraphy.
In the comparison of scintigraphies obtained in the before and just after brain death period, there was impairment of tubular functions, concentration and excretion functions in the postbrain death period.
In the immediate postbrain death period, there was a significant elevation in the glomerular filtration rate and time to maximum concentration values.
In the histopathological evaluation of the kidney samples in the postbrain death period, there were definitive findings of tubular impairment.
Dynamic renal scintigraphy also demonstrated definite impairment of tubular system and tubular functions in the deceased donor kidneys.
This could explain the reason of the increased frequency of acute tubular necrosis seen among deceased donor kidneys
American Psychological Association (APA)
Mitil, Husayn Aydin& Koc, Zehra Pınar& Guzel, Yunus& Kom, Mustafa& Ozer, A. Belin& Balci, Tansel Ansal…[et al.]. 2017. Dynamic renal scintigraphic estimation of deceased donor kidneys in a rat model. Saudi Journal of Kidney Diseases and Transplantation،Vol. 28, no. 2, pp.273-278.
https://search.emarefa.net/detail/BIM-761839
Modern Language Association (MLA)
Balci, Tansel Ansal…[et al.]. Dynamic renal scintigraphic estimation of deceased donor kidneys in a rat model. Saudi Journal of Kidney Diseases and Transplantation Vol. 28, no. 2 (Mar. / Apr. 2017), pp.273-278.
https://search.emarefa.net/detail/BIM-761839
American Medical Association (AMA)
Mitil, Husayn Aydin& Koc, Zehra Pınar& Guzel, Yunus& Kom, Mustafa& Ozer, A. Belin& Balci, Tansel Ansal…[et al.]. Dynamic renal scintigraphic estimation of deceased donor kidneys in a rat model. Saudi Journal of Kidney Diseases and Transplantation. 2017. Vol. 28, no. 2, pp.273-278.
https://search.emarefa.net/detail/BIM-761839
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 277-278
Record ID
BIM-761839