Eculizumab experience in an adult patient with atypical hemolytic uremic syndrome
Joint Authors
Inci, Ayca
Sari, Funda
Yilmaz, Banu
Sarikaya, Metin
Olmaz, Refik
Kurtoglu, Erdal
Karakus, Volkan
Source
Saudi Journal of Kidney Diseases and Transplantation
Issue
Vol. 28, Issue 2 (30 Apr. 2017), pp.388-391, 4 p.
Publisher
Saudi Center for Organ Transplantation
Publication Date
2017-04-30
Country of Publication
Saudi Arabia
No. of Pages
4
Main Subjects
Abstract EN
Atypical hemolytic-uremic syndrome is a disease characterized by nonimmune hemolytic anemia, thrombocytopenia, and renal failure.
In this study, we present a case of a patient with atypical hemolytic-uremic syndrome treated successfully with eculizumab.
A 20- year-old female was admitted with clinical signs of atypical hemolytic syndrome.
The laboratory findings were as follows: hemoglobin 9.2 g/dL, platelet count 18 × 103/μL, creatinine 4.69 mg/dL, schistocytes were in peripheral blood smear, lactate dehydrogenase 2080 U/L, and emergency plasmapheresis procedure with fresh frozen plasma were initiated.
The patient was anuric within 12 h of her admittance.
ADAMTS13 activity was normal.
Her mother’s cousin developed acute rejection immediately after receiving a renal transplant and died two months later.
As she did not respond to the treatment and considering her family history, eculizumab was initiated which resulted in platelet counts starting to rise on day 5, and the patient no longer needed dialysis after 22 days.
American Psychological Association (APA)
Sari, Funda& Inci, Ayca& Karakus, Volkan& Yilmaz, Banu& Sarikaya, Metin& Olmaz, Refik…[et al.]. 2017. Eculizumab experience in an adult patient with atypical hemolytic uremic syndrome. Saudi Journal of Kidney Diseases and Transplantation،Vol. 28, no. 2, pp.388-391.
https://search.emarefa.net/detail/BIM-761930
Modern Language Association (MLA)
Sari, Funda…[et al.]. Eculizumab experience in an adult patient with atypical hemolytic uremic syndrome. Saudi Journal of Kidney Diseases and Transplantation Vol. 28, no. 2 (Mar. / Apr. 2017), pp.388-391.
https://search.emarefa.net/detail/BIM-761930
American Medical Association (AMA)
Sari, Funda& Inci, Ayca& Karakus, Volkan& Yilmaz, Banu& Sarikaya, Metin& Olmaz, Refik…[et al.]. Eculizumab experience in an adult patient with atypical hemolytic uremic syndrome. Saudi Journal of Kidney Diseases and Transplantation. 2017. Vol. 28, no. 2, pp.388-391.
https://search.emarefa.net/detail/BIM-761930
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 390-391
Record ID
BIM-761930