New mixed ligand Zn (II) complexes based on the biologically active substituted acetic acid and nitrogen donor ligands, synthesis, crystal structure and biological applications
Other Title(s)
مركبات جديدة تشمل معدن الزنك ثنائي الشحنة مع حمض الخليك و القواعد النيتروجينية النشطة بيولوجيا، تحضير, التركيب البلوري و التطبيقات البيولوجية
Dissertant
Thesis advisor
Comitee Members
Warad, Ismail Khalil
Abu Khwik, Arwa
University
Birzeit University
Faculty
Faculty of Science
Department
Department of Chemistry
University Country
Palestine (West Bank)
Degree
Master
Degree Date
2016
English Abstract
The complexes [Zn(methoxyacetate)21,10-phenanthroline] 1, [Zn2 (phenylacetate)4(quinoline)2] 2, [Zn (phenylacetate)2(2aminopyridin)] 3, [Zn(phenylacetate)2 1,10-phenanthroline] 4, [Zn(phenylacetate)2 2,9-dimethyl-1,10-phenanthroline] 5 were prepared and characterized by IR-spectroscopy, UV-Visible spectroscopy, 1H and 13C NMR spectroscopy, single crystal X-ray diffraction.
BNPP hydrolysis of the complexes and their parent nitrogen ligands were scanned, the results showed that BNPP hydrolysis were decreased in the order: complex 2 > 4 > 3 > 1 > 5, the results also showed that these complexes can act as a catalysts for phosphate diester hydrolysis. In addition, anti-bacterial activities were scanned to view the effect of complexation on their activity against Gram-positive (S.
epidermidis, S.
aureus, E.
faecalis, M.
luteus and B.
Subtilis) and Gram-negative (K.
pneumonia, E.
coli, P.
Mirabilis and P.
Aeruginosa) bacteria using agar well-diffusion method.
Complex 1 showed high activity against G- and G+ bacteria except against E.
faecalis and P.
Aeruginosa.
Complex 4 showed good activity against G- bacteria except against P.
Aeruginosa, G+ bacteria and against E.
faecalis.
Complex 5 showed zero activity against G- bacteria but low activity against M.
luteus, B.
Subtilis bacteria and high activity against S.
epidermidis and S.
aureus.
Complexes 2 and 3 did not show any activity against G- or G+ bacteria
Main Subjects
No. of Pages
128
Table of Contents
Table of contents.
Abstract.
Abstract in Arabic.
[Chapter One] : Introduction.
[Chapter Two] : Experimental.
[Chapter Three] : Results and discussion.
[Chapter Four] : Conclusion.
References.
American Psychological Association (APA)
Kamil, Shayma Kamal. (2016). New mixed ligand Zn (II) complexes based on the biologically active substituted acetic acid and nitrogen donor ligands, synthesis, crystal structure and biological applications. (Master's theses Theses and Dissertations Master). Birzeit University, Palestine (West Bank)
https://search.emarefa.net/detail/BIM-762562
Modern Language Association (MLA)
Kamil, Shayma Kamal. New mixed ligand Zn (II) complexes based on the biologically active substituted acetic acid and nitrogen donor ligands, synthesis, crystal structure and biological applications. (Master's theses Theses and Dissertations Master). Birzeit University. (2016).
https://search.emarefa.net/detail/BIM-762562
American Medical Association (AMA)
Kamil, Shayma Kamal. (2016). New mixed ligand Zn (II) complexes based on the biologically active substituted acetic acid and nitrogen donor ligands, synthesis, crystal structure and biological applications. (Master's theses Theses and Dissertations Master). Birzeit University, Palestine (West Bank)
https://search.emarefa.net/detail/BIM-762562
Language
English
Data Type
Arab Theses
Record ID
BIM-762562
