Value of positron emission tomography-computed tomography with 18F-fluoro-2-deoxyglucose (18 F-FDG PET CT)‎ in patients with ovarian cancer

Abstract EN

Objectives: This article discusses the current rôle of ‘^F-fluoro-deoxy-glucose (FDG) PET.

CT and intégrâted PET/CT in the management of ovarian cancer patients.

Patients and Methods: 87 PET/CT scans of 64 women with clinicatly suspected or pathologically proven ovarian cancer were analyzed.

The fmdings of contrast enhanced CT (CE-CT) were interpreted by one experienced radiologist unaware of PET/CTfinding.s.

Two experienced nuclear medicine phy.sicians who were imaware of CE-CT findings examined PET images, evaluating localization and characterization and compared them ta co-registered PET/CT images.

Diagnostic accuracy was determined on a patient level and a région level.

Results: PET bas significantly higher Sensitivity, specificity PPV NPV, and overall accuracy (94.7%, 86.7%, 93.1%, 89.7%,, and 91.9% respectively) compared ta (89.5%o, 30%, 70.8%, 60% and 68.9%) for CT on patient level.

The diagnostic performance of PET was also belter at mosl anatomical sites when results were analyzed on région level.

Conclusions and Recommendations: FDG PET in addition to conventional imaging modalities .should represent an important step in the diagnostic flow chart of ovarian cancer patients.

Particularly in patients having a liigh risk for the presence of extra-abdominal metastatic deposits.