Regulation of serum lipid profile, glucose, insulin, and adiponectin in obese diabetic women under diet therapy : a randomized clinical controlled study
Joint Authors
Muhammadi, Sumayyah
Arefhosseini, Sayyid Rafie
Sharifnia, Zarin
Ibrahimi Mameghani, Mehrangiz
Asghari Jafarabadi, Muhammad
Source
Iranian Red Crescent Medical Journal
Issue
Vol. 19, Issue 1 (31 Jan. 2017), pp.1-8, 8 p.
Publisher
Publication Date
2017-01-31
Country of Publication
United Arab Emirates
No. of Pages
8
Main Subjects
Abstract EN
Background: Obesity is the main cause of insulin resistance and type 2 diabetes mellitus (T2DM).
Diet therapy is the cornerstone in the management of obesity and T2DM.
Objectives: We evaluated the effects of calorie-restricted diet therapy on the circulating level of the serum lipid profile, glucose, insulin, and adiponectin in obese women with T2DM.
Materials and Methods: This randomized clinical controlled trial was performed for 10 weeks on 30 eligible obese T2DM women distributed to control (n = 15) and diet therapy (n = 15) groups.
Demographic, nutritional, anthropometric, and laboratory data were obtained before and after the study.
Data were analyzed by SPSS vs.15 and Nutritionist IV.
Results: In addition to anthropometric measurements, diet therapy independently improved fasting blood sugar (P = 0.024, -69.37 to -5.57 mg/dL), 2-h postprandial blood sugar (P = 0.007, -123.34 to -22.3 mg/dL), serum total cholesterol (P = 0.005, -46.48 to -9.72 mg/dL), serum alanine transaminase (P = 0.001, -8.91 to -3.18 U/L), and increased circulating adiponectin (P = 0.038, 0.01 to 0.47 g/mL).
Conclusions: Improvement of biomarkers of insulin sensitivity, including adiponectin and lipid metabolism, is an important therapeutic effect of medical nutrition therapy in obese patients with T2DM.
American Psychological Association (APA)
Muhammadi, Sumayyah& Arefhosseini, Sayyid Rafie& Asghari Jafarabadi, Muhammad& Sharifnia, Zarin& Ibrahimi Mameghani, Mehrangiz. 2017. Regulation of serum lipid profile, glucose, insulin, and adiponectin in obese diabetic women under diet therapy : a randomized clinical controlled study. Iranian Red Crescent Medical Journal،Vol. 19, no. 1, pp.1-8.
https://search.emarefa.net/detail/BIM-766374
Modern Language Association (MLA)
Muhammadi, Sumayyah…[et al.]. Regulation of serum lipid profile, glucose, insulin, and adiponectin in obese diabetic women under diet therapy : a randomized clinical controlled study. Iranian Red Crescent Medical Journal Vol. 19, no. 1 (Jan. 2017), pp.1-8.
https://search.emarefa.net/detail/BIM-766374
American Medical Association (AMA)
Muhammadi, Sumayyah& Arefhosseini, Sayyid Rafie& Asghari Jafarabadi, Muhammad& Sharifnia, Zarin& Ibrahimi Mameghani, Mehrangiz. Regulation of serum lipid profile, glucose, insulin, and adiponectin in obese diabetic women under diet therapy : a randomized clinical controlled study. Iranian Red Crescent Medical Journal. 2017. Vol. 19, no. 1, pp.1-8.
https://search.emarefa.net/detail/BIM-766374
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 7-8
Record ID
BIM-766374