A chronic myeloid leukemia with a unique variant Philadelphia chromosome translocation : t(9; 22; 19) (q34; q11.2; p13)
Joint Authors
Shome, Durjoy K.
Garcia, Wilfredo Roque
Abdel Sohaie, Rihab
Muhammad, Alaa Sayyid
Turani, Jalal Isa
Jahan, Syeeda Khursheed Kousar
Kalim Allah, Muhammad Rahman
Source
Issue
Vol. 39, Issue 4 (31 Dec. 2017), pp.241-243, 3 p.
Publisher
King Hamad University Hospital
Publication Date
2017-12-31
Country of Publication
Bahrain
No. of Pages
3
Main Subjects
Topics
Abstract EN
Chronic myeloid leukemia (CML) is categorized as one of the myeloproliferative neoplasms, according to the World Health Organization (WHO) myeloid neoplasms and acute leukemia classification.
The hallmark of this disease is the presence of a reciprocal translocation between the long arms of chromosomes 9 and 22 [t(9;22)(q34;q11)] which leads to the formation of the Philadelphia chromosome (Ph) and is present in 90%-95% of CML patients.
In 5%-10% of CML cases, there are variants where one or more different chromosomes are involved in addition to chromosome 9 and 22.
We present a patient with newly diagnosed CML with a rare variant translocation involving chromosomes 9, 19 and 22.
To the best of our knowledge, this is the first case study to describe a variant Ph chromosome translocation in chronic phase CML in Bahrain.
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American Psychological Association (APA)
Garcia, Wilfredo Roque& Shome, Durjoy K.& Abdel Sohaie, Rihab& Muhammad, Alaa Sayyid& Turani, Jalal Isa& Jahan, Syeeda Khursheed Kousar…[et al.]. 2017. A chronic myeloid leukemia with a unique variant Philadelphia chromosome translocation : t(9; 22; 19) (q34; q11.2; p13). Bahrain Medical Bulletin،Vol. 39, no. 4, pp.241-243.
https://search.emarefa.net/detail/BIM-766976
Modern Language Association (MLA)
Garcia, Wilfredo Roque…[et al.]. A chronic myeloid leukemia with a unique variant Philadelphia chromosome translocation : t(9; 22; 19) (q34; q11.2; p13). Bahrain Medical Bulletin Vol. 39, no. 4 (Dec. 2017), pp.241-243.
https://search.emarefa.net/detail/BIM-766976
American Medical Association (AMA)
Garcia, Wilfredo Roque& Shome, Durjoy K.& Abdel Sohaie, Rihab& Muhammad, Alaa Sayyid& Turani, Jalal Isa& Jahan, Syeeda Khursheed Kousar…[et al.]. A chronic myeloid leukemia with a unique variant Philadelphia chromosome translocation : t(9; 22; 19) (q34; q11.2; p13). Bahrain Medical Bulletin. 2017. Vol. 39, no. 4, pp.241-243.
https://search.emarefa.net/detail/BIM-766976
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 243
Record ID
BIM-766976