Patterns of glomerulonephritis with crescents : experience at a tertiary medical center in Saudi Arabia
Joint Authors
al-Husayn, Turki
Asiri, Shua
Amir, Sadiq
al-Mana, Hadil
Akhtar, Muhammad
Source
Saudi Journal of Kidney Diseases and Transplantation
Issue
Vol. 28, Issue 3 (30 Jun. 2017), pp.532-537, 6 p.
Publisher
Saudi Center for Organ Transplantation
Publication Date
2017-06-30
Country of Publication
Saudi Arabia
No. of Pages
6
Main Subjects
Topics
Abstract EN
A series of 78 cases of glomerulonephritis (GN), in which renal biopsy revealed changes of GN associated with crescent formation, were reviewed.
Renal pathology findings were correlated with clinical features including patient’s age, renal function, and serologic findings.
In most of the cases (71.8%), the crescents were due to immune complex-mediated GN.
This was followed by pauci-immune GN (20.5%) and anti-glomerular basement membrane antibody (GBM) GN (7.7%).
The percentage of glomeruli with crescents was the highest in cases of anti- GBM disease (mean of 93.3%), followed by pauci-immune GBM (mean of 48.2%) and immune complex GN (30.9%).
In cases with the pauci- immune GN, there were additional features of glomerular injury including fibrinoid necrosis, disruption of the GBM, and rupture of Bowman’s capsule.
These changes were generally more pronounced in a subset of pauci-immune GN associated with serum elevation of antineutrophil cytoplasmic antibody (c-ANCA).
In biopsies from patient with immune complex disease, systemic lupus erythematosus was the most common cause of crescentic GN.
American Psychological Association (APA)
al-Husayn, Turki& Asiri, Shua& Amir, Sadiq& al-Mana, Hadil& Akhtar, Muhammad. 2017. Patterns of glomerulonephritis with crescents : experience at a tertiary medical center in Saudi Arabia. Saudi Journal of Kidney Diseases and Transplantation،Vol. 28, no. 3, pp.532-537.
https://search.emarefa.net/detail/BIM-767430
Modern Language Association (MLA)
al-Husayn, Turki…[et al.]. Patterns of glomerulonephritis with crescents : experience at a tertiary medical center in Saudi Arabia. Saudi Journal of Kidney Diseases and Transplantation Vol. 28, no. 3 (May. / Jun. 2017), pp.532-537.
https://search.emarefa.net/detail/BIM-767430
American Medical Association (AMA)
al-Husayn, Turki& Asiri, Shua& Amir, Sadiq& al-Mana, Hadil& Akhtar, Muhammad. Patterns of glomerulonephritis with crescents : experience at a tertiary medical center in Saudi Arabia. Saudi Journal of Kidney Diseases and Transplantation. 2017. Vol. 28, no. 3, pp.532-537.
https://search.emarefa.net/detail/BIM-767430
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 537
Record ID
BIM-767430