A randomized controlled trial of the effects of hydrochlorothiazide on overactive bladder and idiopathic hypercalciuria
Joint Authors
Durrah, Fatimah
Rafi, Muhammad
Naziri, Mahdiah
Azimnejad, Atifah
Yousefichaijan, Parsa
Source
Saudi Journal of Kidney Diseases and Transplantation
Issue
Vol. 28, Issue 3 (30 Jun. 2017), pp.566-570, 5 p.
Publisher
Saudi Center for Organ Transplantation
Publication Date
2017-06-30
Country of Publication
Saudi Arabia
No. of Pages
5
Main Subjects
Topics
Abstract EN
Overactive bladder is a stressful condition which affects around 15%–20% of 5- year-old and up to 2% of young adults.
One of the most common causes of overactive bladder is hypercalciuria.
Our study investigated the effect of hydrochlorothiazide (HCTZ) on overactive bladder and hypercalciuria.
This randomized controlled trial was conducted on 88 patients with overactive bladder and idiopathic hypercalciuria.
They were randomly divided into the intervention group receiving 1 mg/kg/day of HCTZ for 3 months, and the control group receiving training without any intervention.
Treatment compliance and response were reviewed monthly in each patient using a 30-day bedwetting diary.
In the 1st month, the mean of bedwetting was 14.47 7.06 and 12.61 7.57 in the intervention and control groups, respectively (P = 0.23).
In the 2nd month, it was 10.04 6.32 and 10.79 7.83 in the intervention and control groups, respectively (P = 0.62); and in the 3rd month, it was 6.49 7.13 and 7.64 7.95 in the intervention and control groups, respectively (P = 0.59).
There was no significant difference between the two groups.
Thus, use of HCTZ was not found to be better than urine retention control training.
Therefore, one may conclude that treating hypercalciuria with HCTZ had no demonstrable effect on overactive bladder.
American Psychological Association (APA)
Yousefichaijan, Parsa& Durrah, Fatimah& Rafi, Muhammad& Naziri, Mahdiah& Azimnejad, Atifah. 2017. A randomized controlled trial of the effects of hydrochlorothiazide on overactive bladder and idiopathic hypercalciuria. Saudi Journal of Kidney Diseases and Transplantation،Vol. 28, no. 3, pp.566-570.
https://search.emarefa.net/detail/BIM-767467
Modern Language Association (MLA)
Yousefichaijan, Parsa…[et al.]. A randomized controlled trial of the effects of hydrochlorothiazide on overactive bladder and idiopathic hypercalciuria. Saudi Journal of Kidney Diseases and Transplantation Vol. 28, no. 3 (May. / Jun. 2017), pp.566-570.
https://search.emarefa.net/detail/BIM-767467
American Medical Association (AMA)
Yousefichaijan, Parsa& Durrah, Fatimah& Rafi, Muhammad& Naziri, Mahdiah& Azimnejad, Atifah. A randomized controlled trial of the effects of hydrochlorothiazide on overactive bladder and idiopathic hypercalciuria. Saudi Journal of Kidney Diseases and Transplantation. 2017. Vol. 28, no. 3, pp.566-570.
https://search.emarefa.net/detail/BIM-767467
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 569-570
Record ID
BIM-767467