Primary focal segmental glomerulosclerosis recurring rapidly as collapsing glomerulopathy in a renal allograft recipient
Joint Authors
Singh, Pritpal
Prasad, Narayan
Agrawal, Vinita
Source
Saudi Journal of Kidney Diseases and Transplantation
Issue
Vol. 28, Issue 3 (30 Jun. 2017), pp.621-624, 4 p.
Publisher
Saudi Center for Organ Transplantation
Publication Date
2017-06-30
Country of Publication
Saudi Arabia
No. of Pages
4
Main Subjects
Topics
Abstract EN
Recurrent focal segmental glomerulosclerosis (FSGS) develops in about 30%–40% of patients of FSGS undergoing renal transplantation.
We report a patient who received a liverelated renal transplant for end-stage renal disease due to a primary FSGS (not otherwise specified) in the native kidney and presented with graft dysfunction in the immediate posttransplant period.
The first and the second biopsy showed no evidence of rejection or glomerular lesion.
A repeat biopsy done on the 30th day revealed recurrent FSGS morphologically presenting as collapsing variant.
The patient was found to have massive proteinuria.
Electron microscopy done retrospectively showed glomerular foot process effacement even in the first biopsy.
This case highlights the presence of an early minimal change disease-like phase in recurrent FSGS and the necessity of evaluation for proteinuria even in immediate and early posttransplant period.
It also shows that different variants of FSGS may represent a spectrum of the same disease and suggests a likely role of a pathogenic circulating factor even in collapsing FSGS requiring further evaluation.
American Psychological Association (APA)
Agrawal, Vinita& Prasad, Narayan& Singh, Pritpal. 2017. Primary focal segmental glomerulosclerosis recurring rapidly as collapsing glomerulopathy in a renal allograft recipient. Saudi Journal of Kidney Diseases and Transplantation،Vol. 28, no. 3, pp.621-624.
https://search.emarefa.net/detail/BIM-767513
Modern Language Association (MLA)
Agrawal, Vinita…[et al.]. Primary focal segmental glomerulosclerosis recurring rapidly as collapsing glomerulopathy in a renal allograft recipient. Saudi Journal of Kidney Diseases and Transplantation Vol. 28, no. 3 (May. / Jun. 2017), pp.621-624.
https://search.emarefa.net/detail/BIM-767513
American Medical Association (AMA)
Agrawal, Vinita& Prasad, Narayan& Singh, Pritpal. Primary focal segmental glomerulosclerosis recurring rapidly as collapsing glomerulopathy in a renal allograft recipient. Saudi Journal of Kidney Diseases and Transplantation. 2017. Vol. 28, no. 3, pp.621-624.
https://search.emarefa.net/detail/BIM-767513
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 624
Record ID
BIM-767513