A highly sensitive kinetic-spectrophotometric method for the assay of carbamazepine in pure and commercial tablet

Other Title(s)

طريقة طيفية حركية ذات حساسية عالية لتقدير عقار الكاربامازيبين بصورته النقية و في المستحضرات الصيدلانية

Joint Authors

Zankanah, Fayizah Hazim
Dikran, Sarmad Bahjat

Source

Iraqi Journal of Pharmaceutical Sciences

Issue

Vol. 26, Issue 1 (30 Jun. 2017), pp.1-8, 8 p.

Publisher

University of Baghdad College of Pharmacy

Publication Date

2017-06-30

Country of Publication

Iraq

No. of Pages

8

Main Subjects

Pharmacology

Topics

Abstract EN

The study aimed to recommend a new spectrophotometric-kinetic method for determination of carbamazepine (CABZ) in its pure form and pharmaceutical forms.

The proposed procedure based on the coupling of CABZ with diazotized sulfanilic acid in basic medium to yield a colored azo dye.

Factors affecting the reaction yield were studied and the conditions were optimized.

The colored product was followed spectrophotometrically via monitoring its absorbance at 396 nm.

Under the optimized conditions, two method (the initial rate and fixed time (10 minute)) were applied for constructing the calibration graphs.

The graphs were linear in concentration ranges 2.0 to 18.0 μg.mL-1 for both methods.

The proposed was applied successfully in the determination of CABZ in its commercial formulations.

American Psychological Association (APA)

Dikran, Sarmad Bahjat& Zankanah, Fayizah Hazim. 2017. A highly sensitive kinetic-spectrophotometric method for the assay of carbamazepine in pure and commercial tablet. Iraqi Journal of Pharmaceutical Sciences،Vol. 26, no. 1, pp.1-8.
https://search.emarefa.net/detail/BIM-768872

Modern Language Association (MLA)

Dikran, Sarmad Bahjat& Zankanah, Fayizah Hazim. A highly sensitive kinetic-spectrophotometric method for the assay of carbamazepine in pure and commercial tablet. Iraqi Journal of Pharmaceutical Sciences Vol. 26, no. 1 (2017), pp.1-8.
https://search.emarefa.net/detail/BIM-768872

American Medical Association (AMA)

Dikran, Sarmad Bahjat& Zankanah, Fayizah Hazim. A highly sensitive kinetic-spectrophotometric method for the assay of carbamazepine in pure and commercial tablet. Iraqi Journal of Pharmaceutical Sciences. 2017. Vol. 26, no. 1, pp.1-8.
https://search.emarefa.net/detail/BIM-768872

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references : p. 7-8

Record ID

BIM-768872