A highly sensitive kinetic-spectrophotometric method for the assay of carbamazepine in pure and commercial tablet
Other Title(s)
طريقة طيفية حركية ذات حساسية عالية لتقدير عقار الكاربامازيبين بصورته النقية و في المستحضرات الصيدلانية
Joint Authors
Zankanah, Fayizah Hazim
Dikran, Sarmad Bahjat
Source
Iraqi Journal of Pharmaceutical Sciences
Issue
Vol. 26, Issue 1 (30 Jun. 2017), pp.1-8, 8 p.
Publisher
University of Baghdad College of Pharmacy
Publication Date
2017-06-30
Country of Publication
Iraq
No. of Pages
8
Main Subjects
Topics
Abstract EN
The study aimed to recommend a new spectrophotometric-kinetic method for determination of carbamazepine (CABZ) in its pure form and pharmaceutical forms.
The proposed procedure based on the coupling of CABZ with diazotized sulfanilic acid in basic medium to yield a colored azo dye.
Factors affecting the reaction yield were studied and the conditions were optimized.
The colored product was followed spectrophotometrically via monitoring its absorbance at 396 nm.
Under the optimized conditions, two method (the initial rate and fixed time (10 minute)) were applied for constructing the calibration graphs.
The graphs were linear in concentration ranges 2.0 to 18.0 μg.mL-1 for both methods.
The proposed was applied successfully in the determination of CABZ in its commercial formulations.
American Psychological Association (APA)
Dikran, Sarmad Bahjat& Zankanah, Fayizah Hazim. 2017. A highly sensitive kinetic-spectrophotometric method for the assay of carbamazepine in pure and commercial tablet. Iraqi Journal of Pharmaceutical Sciences،Vol. 26, no. 1, pp.1-8.
https://search.emarefa.net/detail/BIM-768872
Modern Language Association (MLA)
Dikran, Sarmad Bahjat& Zankanah, Fayizah Hazim. A highly sensitive kinetic-spectrophotometric method for the assay of carbamazepine in pure and commercial tablet. Iraqi Journal of Pharmaceutical Sciences Vol. 26, no. 1 (2017), pp.1-8.
https://search.emarefa.net/detail/BIM-768872
American Medical Association (AMA)
Dikran, Sarmad Bahjat& Zankanah, Fayizah Hazim. A highly sensitive kinetic-spectrophotometric method for the assay of carbamazepine in pure and commercial tablet. Iraqi Journal of Pharmaceutical Sciences. 2017. Vol. 26, no. 1, pp.1-8.
https://search.emarefa.net/detail/BIM-768872
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 7-8
Record ID
BIM-768872