Study of the relationship between some microorganism isolated from congenital anomalies neonatal screening and their mothers in Iraqi patient

Abstract EN

Objectives : this study was seeks to determine the Ig G and Ig M in serum mothers and their babies of Iraqi patient suffering from congenital anomalies toward some microorganisms such as Cytomegalovirus (CMV), Congenital toxoplasmosis , Congenital rubella and Genital herpes simplex virus (HSV) correlated with age and babies gender the sample was collected from AL- Alwayia hospital for children / Baghdad .

Methodology : fifth blood sample have been collected from mothers and their babies suffering from congenital anomalies to detection IgG and IgM of some viruses including as Cytomegalovirus (CMV), congenital toxoplasmosis , Congenital rubella and Genital herpes simplex virus (HSV) was diagnosed by , enzyme-linked immunosorbent assay ELISA .

Results : this study was showed that 27 male and 23 female , the mother’s age was 18-33 years old while babies’ s age was 1 day – 18 months , the mean of this study was 24.46 with Std 4.

35 .

The current study was noted the IgG of Congenital Toxoplasmosis in serum of mothers more than their infant at 37 , 20 (74 , 40 ) % respectively as positive result , also the highest frequency for the disease was IgG in mothers more than IgG in male babies of 19, 10 ( 70.37 , 37.04 ) respectively and 18 , 10 ( 78.26 , 43.48 ) respectively in female babies , also the high level of IgM of CMV in babies was 3 ( 6 %) (1 male and 2 female )of positive result distributed as IgM in mothers and baby at 3, 2 ( 11.11 , 8.7 ) % respectively , on the other hand the IgM of HSV in babies was 3 (6 % ) positive result 2 ( 7.41 %) positive result with male babies while 1 ( 4.35 %) with female baby.

Finally the positive result of Rubella infection was with IgM babies at 3(6 %) distributed the positive result was 2 (7.41 %) in male babies and 1 ( 4.35 %) in female baby.