Detection of metallo-β-lactamase producing pseudomonas aeruginosa in clinical isolates from hospitals in Erbil city, Iraqi Kurdistan
Joint Authors
Aka, Safa Tuma Hana
Haji, Sayran H.
Ganjo, Aryan R.
Source
ZANCO Journal of Pure and Applied Sciences
Issue
Vol. 29, Issue 3 (30 Jun. 2017), pp.12-18, 7 p.
Publisher
Salahaddin University-Erbil Department of Scientific Publications
Publication Date
2017-06-30
Country of Publication
Iraq
No. of Pages
7
Main Subjects
Natural & Life Sciences (Multidisciplinary)
Abstract EN
Multidrug resistance (MDR) became a great concern in P.
aeruginosa has appeared as issue of great concern with the emergence of Metallo-β-lactamases (MBL)-producing isolates, which showed to be the primary resistance mechanism in carbapenem-resistant P.
aeruginosa.
The aim of the present study was to detect MBL-producing P.
aeruginosa isolates from patients and evaluating antibiotic guide for clinicians in prescribing accurate antibiotic and to further controlling hospital infections.
A total of 98 consecutive isolates of P.
aeruginosa causing infections were isolated from various clinical samples.
We applied Vitek-2 automated system as a panel of antimicrobial agents.
Imipenem-EDTA combined disk test (CDT) and modified Hodge test (MHT) for phenotypic detection of MBL-producing isolates were followed.
Out of 98 isolates of P.aeruginosa, only 72 isolates (73%) showed IMP-resistance and 26 (26%) were sensitive to imipenem.
Around 63 (87.5%) of the IMP-resistant isolates were able to produce MBLs as determined by CDT, while 30 (41.6%) showed positive results in MHT.
The resistance to tested antibiotics was significantly higher (P <0.001) with MBL producing P.
aeruginosa isolates compared to non-MBL producers.
The prevalence of MDR to the antibiotics among MBL-producing P.
aeruginosa isolates was established.
CDT is a reliable screening test for the detection of MBL producer
American Psychological Association (APA)
Ganjo, Aryan R.& Aka, Safa Tuma Hana& Haji, Sayran H.. 2017. Detection of metallo-β-lactamase producing pseudomonas aeruginosa in clinical isolates from hospitals in Erbil city, Iraqi Kurdistan. ZANCO Journal of Pure and Applied Sciences،Vol. 29, no. 3, pp.12-18.
https://search.emarefa.net/detail/BIM-770825
Modern Language Association (MLA)
Ganjo, Aryan R.…[et al.]. Detection of metallo-β-lactamase producing pseudomonas aeruginosa in clinical isolates from hospitals in Erbil city, Iraqi Kurdistan. ZANCO Journal of Pure and Applied Sciences Vol. 29, no. 3 (2017), pp.12-18.
https://search.emarefa.net/detail/BIM-770825
American Medical Association (AMA)
Ganjo, Aryan R.& Aka, Safa Tuma Hana& Haji, Sayran H.. Detection of metallo-β-lactamase producing pseudomonas aeruginosa in clinical isolates from hospitals in Erbil city, Iraqi Kurdistan. ZANCO Journal of Pure and Applied Sciences. 2017. Vol. 29, no. 3, pp.12-18.
https://search.emarefa.net/detail/BIM-770825
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 17-18.
Record ID
BIM-770825