Vitamin D levels and other biochemical parameters of mineral bone disorders and their association with diastolic dysfunction and left ventricular mass in young no diabetic adult patients with chronic kidney disease
Joint Authors
Sonkar, Satyendra Kumar
Pandey, Sant Kumar
Chandra, Sharad
Bhosale, Vivek
Sonkar, Gyanendra Kumar
Bhutani, Mohit
Source
Saudi Journal of Kidney Diseases and Transplantation
Issue
Vol. 28, Issue 4 (31 Aug. 2017), pp.758-763, 6 p.
Publisher
Saudi Center for Organ Transplantation
Publication Date
2017-08-31
Country of Publication
Saudi Arabia
No. of Pages
6
Main Subjects
Topics
Abstract EN
Cardiovascular disease (CVD) is the leading cause of morbidity and mortality in patients with end-stage renal disease.
Chronic kidney disease (CKD)-associated cardiovascular mortality is more prevalent in those with diastolic heart failure and is an early predictor, while increased left ventricular mass (LVM) is a strong independent risk factor.
Hypovitaminosis D is extensively being studied as a nontraditional risk factor for CVD.
The aim of the present study is to look at the association of Vitamin D and other parameters of mineral bone disorder (MBD) with diastolic dysfunction and LVM in nondiabetic young adult patients with CKD.
This was a hospital-based, cross-sectional observational study.
Groups I and II comprised nondiabetic predialysis CKD patients (stage 4 and 5) and healthy controls, respectively.
Groups IA and IB comprised cases with and without diastolic dysfunction, respectively.
Vitamin D level was measured by enhanced chemiluminescence method and intact parathyroid hormone (iPTH) by electrochemiluminescence method.
Parameters for diastolic function and LVM were assessed by Doppler echocardiography, tissue Doppler imaging, and M-mode echocardiography.
Vitamin D level was significantly lower in Group I as compared to Group II.
Diastolic dysfunction was present in 48.8% of the cases and was significantly associated with serum phosphorus and calcium-phosphorous product, but not with Vitamin D level.
A statistically significant positive
American Psychological Association (APA)
Sonkar, Satyendra Kumar& Bhutani, Mohit& Sonkar, Gyanendra Kumar& Pandey, Sant Kumar& Chandra, Sharad& Bhosale, Vivek. 2017. Vitamin D levels and other biochemical parameters of mineral bone disorders and their association with diastolic dysfunction and left ventricular mass in young no diabetic adult patients with chronic kidney disease. Saudi Journal of Kidney Diseases and Transplantation،Vol. 28, no. 4, pp.758-763.
https://search.emarefa.net/detail/BIM-776113
Modern Language Association (MLA)
Sonkar, Satyendra Kumar…[et al.]. Vitamin D levels and other biochemical parameters of mineral bone disorders and their association with diastolic dysfunction and left ventricular mass in young no diabetic adult patients with chronic kidney disease. Saudi Journal of Kidney Diseases and Transplantation Vol. 28, no. 4 (Jul. / Aug. 2017), pp.758-763.
https://search.emarefa.net/detail/BIM-776113
American Medical Association (AMA)
Sonkar, Satyendra Kumar& Bhutani, Mohit& Sonkar, Gyanendra Kumar& Pandey, Sant Kumar& Chandra, Sharad& Bhosale, Vivek. Vitamin D levels and other biochemical parameters of mineral bone disorders and their association with diastolic dysfunction and left ventricular mass in young no diabetic adult patients with chronic kidney disease. Saudi Journal of Kidney Diseases and Transplantation. 2017. Vol. 28, no. 4, pp.758-763.
https://search.emarefa.net/detail/BIM-776113
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 762-763
Record ID
BIM-776113