Immunoglobulin a nephropathy in a patient with IgG kappa light-chain myeloma
Joint Authors
Aggarwal, Vinita
Kaul, Anupama
Chandra, Abhilash
Source
Saudi Journal of Kidney Diseases and Transplantation
Issue
Vol. 28, Issue 4 (31 Aug. 2017), pp.937-941, 5 p.
Publisher
Saudi Center for Organ Transplantation
Publication Date
2017-08-31
Country of Publication
Saudi Arabia
No. of Pages
5
Main Subjects
Topics
Abstract EN
Paraproteins can cause a variable set of pathologic changes in the kidney.
The introduction of novel anti-plasma cell agents capable of reversing renal failure have revolutionized the management of paraprotein-mediated kidney injury.
Activation of the transcription factor nuclear factor kB (NF-kB) has been shown to be involved in the development of human glomerulonephritis (GN).
Inhibitors of NF-kB may provide potential agents for treatment of immune complex GN.
In this paper, we report a patient with IgA nephropathy and IgG kappa myeloma, who responded dramatically to chemotherapy targeted toward myeloma.
Our findings support the idea that drugs modulating NF-kB may add another dimension to the management of IgA nephropathy
American Psychological Association (APA)
Chandra, Abhilash& Kaul, Anupama& Aggarwal, Vinita. 2017. Immunoglobulin a nephropathy in a patient with IgG kappa light-chain myeloma. Saudi Journal of Kidney Diseases and Transplantation،Vol. 28, no. 4, pp.937-941.
https://search.emarefa.net/detail/BIM-776223
Modern Language Association (MLA)
Chandra, Abhilash…[et al.]. Immunoglobulin a nephropathy in a patient with IgG kappa light-chain myeloma. Saudi Journal of Kidney Diseases and Transplantation Vol. 28, no. 4 (Jul. / Aug. 2017), pp.937-941.
https://search.emarefa.net/detail/BIM-776223
American Medical Association (AMA)
Chandra, Abhilash& Kaul, Anupama& Aggarwal, Vinita. Immunoglobulin a nephropathy in a patient with IgG kappa light-chain myeloma. Saudi Journal of Kidney Diseases and Transplantation. 2017. Vol. 28, no. 4, pp.937-941.
https://search.emarefa.net/detail/BIM-776223
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 940-941
Record ID
BIM-776223