Computational identification and characterization of mirnas and their target genes from five cyprinidae fishes
Joint Authors
Zou, Quan
Huang, Yong
Wang, Yu Qin
Zhang, Ji Liang
Yu, Xue Li
Ren, Hong Tao
Source
Saudi Journal of Biological Sciences
Issue
Vol. 24, Issue 6 (30 Sep. 2017), pp.1126-1135, 10 p.
Publisher
Publication Date
2017-09-30
Country of Publication
Saudi Arabia
No. of Pages
10
Main Subjects
Abstract EN
MicroRNAs (miRNAs) are a kind of small single-strand RNA molecules with lengths of 18–25 nt, which do not encode any proteins.
They play an essential role in gene expression regulation by binding to their target genes, leading to translational repression or transcript degradation.
In this study, 23 miRNAs were predicted from five cyprinidae fishes by using a bioinformatics-based gene search based on blasting ESTs and GSS in NCBI, of which 21 miRNA genes have not been previously reported.
To prove their validity, five of the computationally predicted miRNAs were verified by RTPCR, their transcripts were successfully detected, and, 46 potential target genes for these miRNAs were predicted, most target genes encode transcription factors, they are involved in signal transduction, metabolism and development processes.
American Psychological Association (APA)
Huang, Yong& Ren, Hong Tao& Zou, Quan& Wang, Yu Qin& Zhang, Ji Liang& Yu, Xue Li. 2017. Computational identification and characterization of mirnas and their target genes from five cyprinidae fishes. Saudi Journal of Biological Sciences،Vol. 24, no. 6, pp.1126-1135.
https://search.emarefa.net/detail/BIM-776440
Modern Language Association (MLA)
Huang, Yong…[et al.]. Computational identification and characterization of mirnas and their target genes from five cyprinidae fishes. Saudi Journal of Biological Sciences Vol. 24, no. 6 (Sep. 2017), pp.1126-1135.
https://search.emarefa.net/detail/BIM-776440
American Medical Association (AMA)
Huang, Yong& Ren, Hong Tao& Zou, Quan& Wang, Yu Qin& Zhang, Ji Liang& Yu, Xue Li. Computational identification and characterization of mirnas and their target genes from five cyprinidae fishes. Saudi Journal of Biological Sciences. 2017. Vol. 24, no. 6, pp.1126-1135.
https://search.emarefa.net/detail/BIM-776440
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 1134-1135
Record ID
BIM-776440