The Importance of bone biopsy in chronic kidney disease-mineral bone disorders
Joint Authors
Trigka, Konstantina
Dousdampanis, Periklis
Source
Saudi Journal of Kidney Diseases and Transplantation
Issue
Vol. 28, Issue 5 (31 Oct. 2017), pp.992-996, 5 p.
Publisher
Saudi Center for Organ Transplantation
Publication Date
2017-10-31
Country of Publication
Saudi Arabia
No. of Pages
5
Main Subjects
Topics
Abstract EN
Renal osteodystrophy (ROD) is not a uniform bone disease; it is a heterogeneous group of metabolic bone diseases due to chronic kidney disease (CKD).
The traditional term of ROD does not accurately include the wide spectrum of “CKD–mineral and bone disorder” (CKD–MBD) and has been restricted to define the several specific histologic disturbances of bone disease associated with CKD.
Circulating parathyroid hormone (PTH) and total alkaline phosphatase levels do not always reflect bone turnover in CKD–MBD, whereas bone biopsy provides precise information regarding bone pathology.
Given the lack of specificity of several biomarkers and noninvasive tools regarding ROD, bone biopsy is required for precise diagnosis and for the determination of therapeutic strategies.
In clinical practice, bone biopsy is not performed due to lack of enthusiasm among nephrologists for several reasons including the invasiveness of the procedure, the potential pain, and lack of technical training.
Since the application of bone biopsy in clinical practice is unrealistic, several biomarkers with specificity for bone disease should be studied.
American Psychological Association (APA)
Dousdampanis, Periklis& Trigka, Konstantina. 2017. The Importance of bone biopsy in chronic kidney disease-mineral bone disorders. Saudi Journal of Kidney Diseases and Transplantation،Vol. 28, no. 5, pp.992-996.
https://search.emarefa.net/detail/BIM-776858
Modern Language Association (MLA)
Dousdampanis, Periklis& Trigka, Konstantina. The Importance of bone biopsy in chronic kidney disease-mineral bone disorders. Saudi Journal of Kidney Diseases and Transplantation Vol. 28, no. 5 (Sep. / Oct. 2017), pp.992-996.
https://search.emarefa.net/detail/BIM-776858
American Medical Association (AMA)
Dousdampanis, Periklis& Trigka, Konstantina. The Importance of bone biopsy in chronic kidney disease-mineral bone disorders. Saudi Journal of Kidney Diseases and Transplantation. 2017. Vol. 28, no. 5, pp.992-996.
https://search.emarefa.net/detail/BIM-776858
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 995-996
Record ID
BIM-776858