Long-term evaluation of kidney function in live-related kidney donors
Joint Authors
Mehta, Kalpana S.
Swami, Rudramani
Pajai, Atim
Bhurke, Sandip
Shirkande, Abhishek
Jawle, Sunil
Source
Saudi Journal of Kidney Diseases and Transplantation
Issue
Vol. 28, Issue 5 (31 Oct. 2017), pp.1041-1049, 9 p.
Publisher
Saudi Center for Organ Transplantation
Publication Date
2017-10-31
Country of Publication
Saudi Arabia
No. of Pages
9
Main Subjects
Topics
Abstract EN
The consequences of live kidney donation on the donor health with main emphasis on postdonation blood pressure (BP), proteinuria, kidney size, and glomerular filtration rate (GFR) were evaluated.
Twenty-five donors with minimum of six months postdonation duration were included in the study.
Donor age at nephrectomy, duration postnephrectomy, systolic and diastolic BP measurement pre- and post-donation, postdonation, blood urea nitrogen, serum creatinine and 24-h proteinuria, blood sugar, two-dimensional echocardiogram were recorded.
Kidney sizes preand post-donation were noted.
GFR was calculated by chronic kidney disease epidemiology collaboration and modification of diet in renal disease formula and measured by diethylene triamine pentaacetic acid renogram in all donors pre- and post-donation.
Twenty-one (84 %) were female, and four (16 %) were male.
The mean age at donation was 46.24 ± 9.62 (28–65) years.
Median duration postdonor nephrectomy was 26 (minimum 7 and maximum 228) months.
There was a mean rise of 6.24 mm Hg in systolic and 4.20 mm Hg diastolic BP (P = 0.001).
Remnant kidney size increased from 35.12 ± 6.80 to 42.32 ± 8.59 sq cm (P <0.0001).
There was reduction of postdonation GFR from 94.50 ± 18.12 mL / min to 60.48 ± 14.32 mL / min after nephrectomy (P <0.0001).
There was significant increase in remnant kidney GFR from 48.83 ± 7.79 mL / min to 60.48 ± 14.32 mL / min (P <0.0001).
Two donors had hypertension postdonation while 23 did not.
No donor developed postdonation proteinuria.
A significant increase in the kidney size and GFR was evident in remnant native kidney in all.
No mortality was observed.
American Psychological Association (APA)
Mehta, Kalpana S.& Swami, Rudramani& Pajai, Atim& Bhurke, Sandip& Shirkande, Abhishek& Jawle, Sunil. 2017. Long-term evaluation of kidney function in live-related kidney donors. Saudi Journal of Kidney Diseases and Transplantation،Vol. 28, no. 5, pp.1041-1049.
https://search.emarefa.net/detail/BIM-776885
Modern Language Association (MLA)
Mehta, Kalpana S.…[et al.]. Long-term evaluation of kidney function in live-related kidney donors. Saudi Journal of Kidney Diseases and Transplantation Vol. 28, no. 5 (Sep. / Oct. 2017), pp.1041-1049.
https://search.emarefa.net/detail/BIM-776885
American Medical Association (AMA)
Mehta, Kalpana S.& Swami, Rudramani& Pajai, Atim& Bhurke, Sandip& Shirkande, Abhishek& Jawle, Sunil. Long-term evaluation of kidney function in live-related kidney donors. Saudi Journal of Kidney Diseases and Transplantation. 2017. Vol. 28, no. 5, pp.1041-1049.
https://search.emarefa.net/detail/BIM-776885
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 1048-1049
Record ID
BIM-776885