Evaluation of cephalopoda extract against some nosocomial bacterial isolates
Other Title(s)
تقيم خلاصة قدمية الرأس ضد بعض العزولات البكتيرية المسببة لأمراض المستشفيات
Author
Source
Issue
Vol. 8, Issue 1 (31 Dec. 2014)14 p.
Publisher
University of Thi-Qar College of Medicine
Publication Date
2014-12-31
Country of Publication
Iraq
No. of Pages
14
Main Subjects
Abstract EN
To evaluate the pathogenicity of Staphylococcus aureus and Escherichia coli in male mice and to compare between antibacterial activity Cefotaxime 250mg and cephalopoda extract (Sepia sp.) and showed the effect on some blood parameters in male mice.
The mice were divided into seven groups (six mice for each) ,all treatments were given intraperitoneally to experimental mice.
First group (control animals) were injected with 0.9 % normal saline (0.1 ml for each animal), second group were received i.p.
single dose of E.
coli (0.1× 108 CFU), third group were injected with a single dose of S.
aureus (0.1× 108 CFU), fourth group were injected with a single dose of E.
coli (0.1× 108 CFU) then treated with (0.1 Cefotaxime 250mg) for 3 days fifth group were injected with a single dose of S.
aureus (0.1× 108 CFU) then treated with (0.1 Cefotaxime 250mg) for 3 days, sixth group were injected with a single dose of Escherichia coli (0.1× 108 CFU) then injected with (0.1 of extract,720 μg for each animal ) for 3 days, seventh group were injected i.p.
with a single dose of S.
aureus (0.1× 108 CFU) then injected with (0.1 of extract, 720 μg for each animal ) for 3 days.
The results conducted that all infected mice were suffered from elevated in their body temperatures, while decline in their body weights and subsequently, changes in blood parameters compared with normal value.
On the other hand, treated mice with Sepia extract show healthy and maintained their body temperatures and body weights as normal, in addition to blood parameters remained within normal ranges.
These above results explained the role of Sepia extract as antimicrobial substance, acting against nosocomial bacterial isolates
American Psychological Association (APA)
al-Maliki, Haydar Khamis. 2014. Evaluation of cephalopoda extract against some nosocomial bacterial isolates. Thi-Qar Medical Journal،Vol. 8, no. 1.
https://search.emarefa.net/detail/BIM-779228
Modern Language Association (MLA)
al-Maliki, Haydar Khamis. Evaluation of cephalopoda extract against some nosocomial bacterial isolates. Thi-Qar Medical Journal Vol. 8, no. 1 (2014).
https://search.emarefa.net/detail/BIM-779228
American Medical Association (AMA)
al-Maliki, Haydar Khamis. Evaluation of cephalopoda extract against some nosocomial bacterial isolates. Thi-Qar Medical Journal. 2014. Vol. 8, no. 1.
https://search.emarefa.net/detail/BIM-779228
Data Type
Journal Articles
Language
English
Notes
Includes appendices.
Record ID
BIM-779228