Expression of transforming growth factor alpha and their receptor (EGFR) in thyroid carcinoma and benign patients
Other Title(s)
تعبير البروتين TGF-ألفا و مستقبله EGFR في مرضى السرطان و الأورام الحميدة للغدة الدرقية
Joint Authors
Nasir, Tahani Abd al-Jabbar
Ghali, Karim Hamad
Musa, Hamid Naim
Source
Issue
Vol. 12, Issue 2 (31 Dec. 2016), pp.11-23, 13 p.
Publisher
University of Thi-Qar College of Medicine
Publication Date
2016-12-31
Country of Publication
Iraq
No. of Pages
13
Main Subjects
Topics
Abstract EN
The current study was included 178 patients, 111 patients out them were affected with thyroid cancer, 46 patients were benign neoplastic and 21 individuals were no cancers and benign as control group.
The study was carried out in Laboratory of College of Science, University of Wasit in collaboration with AL-Hussein Teaching Hospital and Ibn al-Bitar Laboratory Specialist in Thi Qar Province, from January 2015 to April 2016.
Immunohistochemical technique was used to determination the expression of TGFα and their receptor EGFR in all studied cases.
The study aimed to estimation the expression of these proteins in thyroid carcinogenesis and the possibility of transforming the benign patients to thyroid cancer.
The results showed overexpression in TGFα in thyroid cancer when compared with benign patients and control group with significant differences (p< 0.05).
Regarding EGFR, the results explained no significant differences when compared between three samples.
Our results concluded there is a strong relationship between TGFα overexpression and thyroid carcinogenesis.
American Psychological Association (APA)
Nasir, Tahani Abd al-Jabbar& Ghali, Karim Hamad& Musa, Hamid Naim. 2016. Expression of transforming growth factor alpha and their receptor (EGFR) in thyroid carcinoma and benign patients. Thi-Qar Medical Journal،Vol. 12, no. 2, pp.11-23.
https://search.emarefa.net/detail/BIM-779265
Modern Language Association (MLA)
Nasir, Tahani Abd al-Jabbar…[et al.]. Expression of transforming growth factor alpha and their receptor (EGFR) in thyroid carcinoma and benign patients. Thi-Qar Medical Journal Vol. 12, no. 2 (2016), pp.11-23.
https://search.emarefa.net/detail/BIM-779265
American Medical Association (AMA)
Nasir, Tahani Abd al-Jabbar& Ghali, Karim Hamad& Musa, Hamid Naim. Expression of transforming growth factor alpha and their receptor (EGFR) in thyroid carcinoma and benign patients. Thi-Qar Medical Journal. 2016. Vol. 12, no. 2, pp.11-23.
https://search.emarefa.net/detail/BIM-779265
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 20-22
Record ID
BIM-779265