Evaluation the protective effect of catharanthusroseus extract on induced peptic ulcer in male rabbits
Other Title(s)
تقييم الفعالية الدفاعية لمستخلص نبات العناقية على القرحة المعوية المصطنعة في ذكور الأرانب
Author
Source
Issue
Vol. 13, Issue 4 (31 Dec. 2016), pp.762-771, 10 p.
Publisher
University of Babylon College of Medicine
Publication Date
2016-12-31
Country of Publication
Iraq
No. of Pages
10
Main Subjects
Abstract EN
The goal of this study is to evaluate the role of Catharanthusroseus alcoholic extraction for treatment of induced peptic ulcer in male rabbits in which there was thirty male , the animals was divided in five groups normal control given only distal water, active control given 500 mg/kg acetyl salsylic acid orally, standard group received single dose 20mg/kg IP of omeprazole follow by 500mg/kg acetyl salsylic acid, the fourth and fifth group received 20, 30mg/kg subsequently ofC.
roseusextract orally by stomach tube one hour before acetyl salsylic acid 500mg/kg orally, macroscopically significant protective effect of C.roseus extract show in dose of 30mg/kg about 61.97%, microscopically in both 20,30mg/kg the sign of healing process were detected which was approximately same as that appear in the standard group, measuring serum level of pro-inflammatory cytokines (IL-4and IL-8),showed there was significant reduction in there level at same level in both doses ,so as conclusion the alcoholic extraction of C.roseus had an antiulcerognic effect with significant reduction in the both IL-4 and IL-8.
American Psychological Association (APA)
Kazim, Rusul Ali. 2016. Evaluation the protective effect of catharanthusroseus extract on induced peptic ulcer in male rabbits. Medical Journal of Babylon،Vol. 13, no. 4, pp.762-771.
https://search.emarefa.net/detail/BIM-779295
Modern Language Association (MLA)
Kazim, Rusul Ali. Evaluation the protective effect of catharanthusroseus extract on induced peptic ulcer in male rabbits. Medical Journal of Babylon Vol. 13, no. 4 (Dec. 2016), pp.762-771.
https://search.emarefa.net/detail/BIM-779295
American Medical Association (AMA)
Kazim, Rusul Ali. Evaluation the protective effect of catharanthusroseus extract on induced peptic ulcer in male rabbits. Medical Journal of Babylon. 2016. Vol. 13, no. 4, pp.762-771.
https://search.emarefa.net/detail/BIM-779295
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 770-771
Record ID
BIM-779295