Effect of exam stress on salivary interleukin-6 level in healthy students

Abstract EN

Cytokines are important small protein molecules one of them is Interleukin-6 (IL-6) .Many tissues secretes IL6 like activated leukocytes .In immune system , IL6 plays main role in production of acute-phase proteins like Creactive protein .

Human labial salivary glands, contain Messenger RNA for IL-6 .

Aim of study was to demonstrate the effect of exam stress onsalivary concentrations of interleukin- 6 (IL-6) in healthy secondary school students .

Salivary specimens were collected from thirteen male students before and after final academic exam.

Cytokine levels were measured by commercial enzyme linked immunoassay.

Salivary IL-6 was insignificantly higher after final exam when compared with its level before exam.

(P >0.05).

students after exam have increased level of inflammatory cytokine (IL-6) in their saliva.

TheIL6 level may be used for monitoring the stress.