Flow injection determination of diclofenac sodium in pharmaceutical formulations based on its inhibiting effect on the chemiluminescent reaction of basic permanganate-luminol
Author
Source
ZANCO Journal of Pure and Applied Sciences
Issue
Vol. 29, Issue 1 (28 Feb. 2017), pp.11-22, 12 p.
Publisher
Salahaddin University-Erbil Department of Scientific Publications
Publication Date
2017-02-28
Country of Publication
Iraq
No. of Pages
12
Main Subjects
Topics
Abstract EN
A reverse flow injection – chemiluminescence (FI-CL) method is described for the determination of diclofenac sodium (DS).
The method based on the quenching effect of DS on the CL light generated from potassium permanganate-luminol system in basic medium.
The optimum conditions for the chemiluminescence emission were investigated.
The calibration graph relating to the ΔCL signal intensity (Δpeak height as a function of CL intensity) vs.
the concentration of the DS was linear and it is suitable for determining DS in the range of 5.0 – 45.0 μg/mL, with the detection limit of 2.5 μg/mL and coefficient of determination 0.9962.
The method was applied successfully for determination of DS in pharmaceutical formulations and compared with high performance liquid chromatography method as a reference method.
F and t tests were calculated and seen that they were less than the tabulated values at 95% confidence level.
American Psychological Association (APA)
Jabbar, Hijran Sinan. 2017. Flow injection determination of diclofenac sodium in pharmaceutical formulations based on its inhibiting effect on the chemiluminescent reaction of basic permanganate-luminol. ZANCO Journal of Pure and Applied Sciences،Vol. 29, no. 1, pp.11-22.
https://search.emarefa.net/detail/BIM-780030
Modern Language Association (MLA)
Jabbar, Hijran Sinan. Flow injection determination of diclofenac sodium in pharmaceutical formulations based on its inhibiting effect on the chemiluminescent reaction of basic permanganate-luminol. ZANCO Journal of Pure and Applied Sciences Vol. 29, no. 1 (2017), pp.11-22.
https://search.emarefa.net/detail/BIM-780030
American Medical Association (AMA)
Jabbar, Hijran Sinan. Flow injection determination of diclofenac sodium in pharmaceutical formulations based on its inhibiting effect on the chemiluminescent reaction of basic permanganate-luminol. ZANCO Journal of Pure and Applied Sciences. 2017. Vol. 29, no. 1, pp.11-22.
https://search.emarefa.net/detail/BIM-780030
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 20-22
Record ID
BIM-780030
