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Comparative analysis of conventional and biological treatment in healing of bone disease
Joint Authors
Lu, Lu
Guo, Wen Zhe
Di, Hui
Chu, Guo Hua
Source
Saudi Journal of Biological Sciences
Issue
Vol. 25, Issue 1 (31 Jan. 2018), pp.162-166, 5 p.
Publisher
Publication Date
2018-01-31
Country of Publication
Saudi Arabia
No. of Pages
5
Main Subjects
Natural & Life Sciences (Multidisciplinary)
Abstract EN
The healing of Bone tissue consists of a complex process.
Hence, we designed our study to evaluate chondrial diseases, which are as they have a very low healing capacity.
Seventy two elderly osteoarthritis (OA) and 54-paediatric juvenile idiopathic arthritis (JIA) patients were included.
The group was divided as 24 OA patients and 18 JIA patients in each group.
Group I received Hyualuronic acid and glucocorticoides.
Group II received platelet rich plasma and fibrin glue.
Group III received PRP, fibrin glue, and MSC.
40 control patients received only PRP treatment.
Out of 72 OA patients 35 (48.6%) male and 37 (51.4%) female with mean age of 48 ± 6.5 years.
64 (88.9%) Patients had pain and swelling.
52 (72.2%) lacked flexibility.
42 (58.3%) had hypertrophy.
28 (38.9%) had less cartilage thickness.
34 (47.2 %) were in grade 3, grade 2 has 28 (38.9%) and grade 1 has 10 (13.9%) patients respectively.
Among 54 JIA patients 28 (51.9%) male and 26 (48.1%) female patients with mean, age 4.6 ± 3.8 years.
39 (72.2%) had pain and swelling.
32 (59.3%) lacked flexibility.
29 (53.7%) children’s had functional disability.
Group I patients showed 30% improvement with no statistical significance (P < 0.21).
Group II showed 45% improvement with statistical significance (P < 0.01).
In Group III 80%, improvement was observed with statistical significance (P < 0.001).
In 40 control patients, 60% improvement was observed.
In conclusion, use of these MSC, PRP, and PPP are safe and less cost effective for treating OA and JIA.
American Psychological Association (APA)
Guo, Wen Zhe& Di, Hui& Chu, Guo Hua& Lu, Lu. 2018. Comparative analysis of conventional and biological treatment in healing of bone disease. Saudi Journal of Biological Sciences،Vol. 25, no. 1, pp.162-166.
https://search.emarefa.net/detail/BIM-780402
Modern Language Association (MLA)
Guo, Wen Zhe…[et al.]. Comparative analysis of conventional and biological treatment in healing of bone disease. Saudi Journal of Biological Sciences Vol. 25, no. 1 (Jan. 2018), pp.162-166.
https://search.emarefa.net/detail/BIM-780402
American Medical Association (AMA)
Guo, Wen Zhe& Di, Hui& Chu, Guo Hua& Lu, Lu. Comparative analysis of conventional and biological treatment in healing of bone disease. Saudi Journal of Biological Sciences. 2018. Vol. 25, no. 1, pp.162-166.
https://search.emarefa.net/detail/BIM-780402
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 165-166
Record ID
BIM-780402