Chitosan treatment for skin ulcers associated with diabetes

Joint Authors

Escarcega Galaz, Ana Aglahe
Cruz Mercado, Jose Luis De La
Lopez Cervantes, Jaime
Sanchez Machado, Dalia Isabel
Brito Zurita, Olga Rosa
Ornelas Aguirre, Jose Manuel

Source

Saudi Journal of Biological Sciences

Issue

Vol. 25, Issue 1 (31 Jan. 2018), pp.130-135, 6 p.

Publisher

Saudi Biological Society

Publication Date

2018-01-31

Country of Publication

Saudi Arabia

No. of Pages

6

Main Subjects

Natural & Life Sciences (Multidisciplinary)

Abstract EN

Infections, ulcerations, gangrene and, in severe cases, extremity amputation, are common complications among diabetic subjects.

Various biomaterials have been utilized for the treatment of these lesions.

Chitosan is an amino sugar with a low risk of toxicity and immune response.

In this study, we evaluated chitosan topical gel and film treatments for subjects with diabetic ulcerations and wounds associated with diabetes mellitus.

In a pre-experimental design, we described the result of chitosan gel and film treatment for wounds and skin ulcers among patients with long-standing diabetes mellitus.

We studied 8 diabetic patients with wounds and skin ulcers (long duration and Wagner degree 1–2).

Initially, most lesions had some degree of infection, tissue damage and ulceration.

At the end of the treatment (topical chitosan) period, the infections were cured.

All patients experienced a significant improvement in the initial injury and developed granulation tissue and a healthy skin cover.

This report represents one of the few published clinical experience regarding the chitosan for the treatment of skin lesions among diabetic subjects.

These results are relevant and promising for the treatment of this disease.

American Psychological Association (APA)

Escarcega Galaz, Ana Aglahe& Cruz Mercado, Jose Luis De La& Lopez Cervantes, Jaime& Sanchez Machado, Dalia Isabel& Brito Zurita, Olga Rosa& Ornelas Aguirre, Jose Manuel. 2018. Chitosan treatment for skin ulcers associated with diabetes. Saudi Journal of Biological Sciences،Vol. 25, no. 1, pp.130-135.
https://search.emarefa.net/detail/BIM-780497

Modern Language Association (MLA)

Escarcega Galaz, Ana Aglahe…[et al.]. Chitosan treatment for skin ulcers associated with diabetes. Saudi Journal of Biological Sciences Vol. 25, no. 1 (Jan. 2018), pp.130-135.
https://search.emarefa.net/detail/BIM-780497

American Medical Association (AMA)

Escarcega Galaz, Ana Aglahe& Cruz Mercado, Jose Luis De La& Lopez Cervantes, Jaime& Sanchez Machado, Dalia Isabel& Brito Zurita, Olga Rosa& Ornelas Aguirre, Jose Manuel. Chitosan treatment for skin ulcers associated with diabetes. Saudi Journal of Biological Sciences. 2018. Vol. 25, no. 1, pp.130-135.
https://search.emarefa.net/detail/BIM-780497

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references : p. 134-135

Record ID

BIM-780497