Evaluation of traditional medicinal plant, cissus setosa roxb. (vitaceae) for antiulcer property
Joint Authors
Paulsamy, Subramaniam
Jayachitra, Chinnamaruthu
Jamuna, Senguttuvan
Ali, Muhammad Ajmal
al-Hamid, Fahd M. A.
Source
Saudi Journal of Biological Sciences
Issue
Vol. 25, Issue 2 (28 Feb. 2018), pp.293-297, 5 p.
Publisher
Publication Date
2018-02-28
Country of Publication
Saudi Arabia
No. of Pages
5
Main Subjects
Topics
Abstract EN
Cissus setosa is an indigenous medicinal herb commonly used for the treatment of gastro ulcers.
In the current investigation the aerial methanolic extract of C.
setosa was investigated for their antiulcer activity using pylorus ligation and ethanol in experimental rats.
The extract was administered at the doses of 200 and 400 mg / kg b.w.
orally for 3 days.
However, higher dose of the extract subsequently reduced gastric ulcer induced aberrations by pylorus ligation (70.05 %) and ethanol (78.16 %) as judged by their altered biochemical parameters such as free acidity, total acidity, total carbohydrate, total protein and pepsin activity.
Furthermore, macroscopic examination of rat’s stomach also showed that the pretreatment with methanolic extract notably lowered the pylorus ligation and ethanol induced ulcers.
As perceived in the present study, evidently, our findings basically supports the potency of the methanol extracts of C.
setosa to treat gastrointestinal related disorders, thus lends pharmacological credence to the suggested folklore use.
American Psychological Association (APA)
Jayachitra, Chinnamaruthu& Jamuna, Senguttuvan& Ali, Muhammad Ajmal& Paulsamy, Subramaniam& al-Hamid, Fahd M. A.. 2018. Evaluation of traditional medicinal plant, cissus setosa roxb. (vitaceae) for antiulcer property. Saudi Journal of Biological Sciences،Vol. 25, no. 2, pp.293-297.
https://search.emarefa.net/detail/BIM-780539
Modern Language Association (MLA)
Jayachitra, Chinnamaruthu…[et al.]. Evaluation of traditional medicinal plant, cissus setosa roxb. (vitaceae) for antiulcer property. Saudi Journal of Biological Sciences Vol. 25, no. 2 (Feb. 2018), pp.293-297.
https://search.emarefa.net/detail/BIM-780539
American Medical Association (AMA)
Jayachitra, Chinnamaruthu& Jamuna, Senguttuvan& Ali, Muhammad Ajmal& Paulsamy, Subramaniam& al-Hamid, Fahd M. A.. Evaluation of traditional medicinal plant, cissus setosa roxb. (vitaceae) for antiulcer property. Saudi Journal of Biological Sciences. 2018. Vol. 25, no. 2, pp.293-297.
https://search.emarefa.net/detail/BIM-780539
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 297
Record ID
BIM-780539