Early predictive value of cord blood bilirubin and dynamic monitoring of transcutaneous bilirubin for hyperbilirubinemia of newborns
Joint Authors
Xu, Hongbo
Li, Hong
Luo, Jian
Wang, Yuan
Guan, Haishan
Lin, Longbin
Xiao, Yifeng
Source
Saudi Journal of Biological Sciences
Issue
Vol. 24, Issue 8 (31 Dec. 2017), pp.1879-1883, 5 p.
Publisher
Publication Date
2017-12-31
Country of Publication
Saudi Arabia
No. of Pages
5
Main Subjects
Natural & Life Sciences (Multidisciplinary)
Abstract EN
Objective : to study the early predictive value of cord blood bilirubin and dynamic monitoring of transcutaneous bilirubin for hyperbilirubinemia of newborns.
Methods : 389 newborns delivered from June 2014 to December 2015 were enrolled as the research subjects ; detailed records were made about the general data of newborns and mothers, and after cord blood bilirubin being graded, the incidence of hyperbilirubinemia was counted, and the prediction efficiency of cord blood bilirubin was analyzed by receiver operator characteristic (ROC) curve.
At the same time, the transcutaneous bilirubin was detected continuously when the neonate was born and 24 h, 48 h and 72 h after birth, and the relativity between transcutaneous bilirubin at 72 h and serum bilirubin was analyzed.
Results: No significant difference was found in the hyperbilirubinemia group and the nonhyperbilirubinemia group concerning general data of the newborns and their mothers.
With the concentration of cord blood bilirubin increased, the incidence of hyperbilirubinemia also increased; separate prediction of hyperbilirubinemia by cord blood bilirubin showed a sensitivity and specificity of 71.4 % and 65.6 % respectively, and they need further dynamic monitoring.
The daily mean of transcutaneous bilirubin in hyperbilirubinemia group was significantly higher than that in non-hyperbilirubinemia group at 24 h, 48 h and 72 h, and the measurement value of transcutaneous bilirubin at 72 h had a high correlation with serum bilirubin.
When transcutaneous bilirubin value is higher than 18, the incidence of hyperbilirubinemia should be considered.
Conclusions : the increase of cord blood bilirubin effectively predict the occurrence of neonatal hyperbilirubinemia.
There is a good correlation between levels of transcutaneous bilirubin and serum bilirubin.
Moreover, combined detection of transcutaneous bilirubin and cord blood bilirubin can significantly improve the prediction accuracy of hyperbilirubinemia.
American Psychological Association (APA)
Guan, Haishan& Li, Hong& Luo, Jian& Lin, Longbin& Wang, Yuan& Xiao, Yifeng…[et al.]. 2017. Early predictive value of cord blood bilirubin and dynamic monitoring of transcutaneous bilirubin for hyperbilirubinemia of newborns. Saudi Journal of Biological Sciences،Vol. 24, no. 8, pp.1879-1883.
https://search.emarefa.net/detail/BIM-780615
Modern Language Association (MLA)
Guan, Haishan…[et al.]. Early predictive value of cord blood bilirubin and dynamic monitoring of transcutaneous bilirubin for hyperbilirubinemia of newborns. Saudi Journal of Biological Sciences Vol. 24, no. 8 (Dec. 2017), pp.1879-1883.
https://search.emarefa.net/detail/BIM-780615
American Medical Association (AMA)
Guan, Haishan& Li, Hong& Luo, Jian& Lin, Longbin& Wang, Yuan& Xiao, Yifeng…[et al.]. Early predictive value of cord blood bilirubin and dynamic monitoring of transcutaneous bilirubin for hyperbilirubinemia of newborns. Saudi Journal of Biological Sciences. 2017. Vol. 24, no. 8, pp.1879-1883.
https://search.emarefa.net/detail/BIM-780615
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 1883
Record ID
BIM-780615