Medically important carotenoids from Momordica charantia and their gene expressions in different organs
Joint Authors
Arasu, Mariadhas Valan
Cuong, Do Manh
Jeon, Jin
Park, Yun Ji
Kwon, Soon Jae
al-Dhabi, Nayif Abd Allah
Park, Sang Un
Source
Saudi Journal of Biological Sciences
Issue
Vol. 24, Issue 8 (31 Dec. 2017), pp.1913-1919, 7 p.
Publisher
Publication Date
2017-12-31
Country of Publication
Saudi Arabia
No. of Pages
7
Main Subjects
Natural & Life Sciences (Multidisciplinary)
Abstract EN
Carotenoids, found in the fruit and different organs of bitter melon (Momordica charantia), have attracted great attention for their potential health benefits in treating several major chronic diseases.
Therefore, study related to the identification and quantification of the medically important carotenoid metabolites is highly important for the treatment of various disorderes.
The present study involved in the identification and quantification of the various carotenoids present in the different organs of M.
charantia and the identification of the genes responsible for the accumulation of the carotenoids with respect to the transcriptome levels were investigated.
In this study, using the transcriptome database of bitter melon, a partial-length cDNA clone encoding geranylgeranyl pyrophosphate synthase (McGGPPS2), and several full-length cDNA clones encoding geranylgeranyl pyrophosphate synthase (McGGPPS1), zeta-carotene desaturase (McZDS), lycopene beta-cyclase (McLCYB), lycopene epsilon cyclases (McLCYE1 and McLCYE2), beta-carotene hydroxylase (McCHXB), and zeaxanthin epoxidase (McZEP) were identified in bitter melon.
The expression levels of the mRNAs encoding these eight putative biosynthetic enzymes, as well as the accumulation of lycopene, a-carotene, lutein, 13Z-b-carotene, E-b-carotene, 9Z-b-carotene, b-cryptoxanthin, zeaxanthin, antheraxanthin, and violaxanthin were investigated in different organs from M.
charantia as well as in the four different stages of its fruit maturation.
Transcripts were found to be constitutively expressed at high levels in the leaves where carotenoids were also found at the highest levels.
Collectively, these results indicate that the putative McGGPPS2, McZDS, McLCYB, McLCYE1, McLCYE2, and McCHXB enzymes might be key factors in controlling carotenoid content in bitter melon.
In conclusion, the over expression of the carotenoid biosynthetic genes from M.
charantia crops to increase the yield of these medically important carotenoids.
American Psychological Association (APA)
Cuong, Do Manh& Arasu, Mariadhas Valan& Jeon, Jin& Park, Yun Ji& Kwon, Soon Jae& al-Dhabi, Nayif Abd Allah…[et al.]. 2017. Medically important carotenoids from Momordica charantia and their gene expressions in different organs. Saudi Journal of Biological Sciences،Vol. 24, no. 8, pp.1913-1919.
https://search.emarefa.net/detail/BIM-780619
Modern Language Association (MLA)
Cuong, Do Manh…[et al.]. Medically important carotenoids from Momordica charantia and their gene expressions in different organs. Saudi Journal of Biological Sciences Vol. 24, no. 8 (Dec. 2017), pp.1913-1919.
https://search.emarefa.net/detail/BIM-780619
American Medical Association (AMA)
Cuong, Do Manh& Arasu, Mariadhas Valan& Jeon, Jin& Park, Yun Ji& Kwon, Soon Jae& al-Dhabi, Nayif Abd Allah…[et al.]. Medically important carotenoids from Momordica charantia and their gene expressions in different organs. Saudi Journal of Biological Sciences. 2017. Vol. 24, no. 8, pp.1913-1919.
https://search.emarefa.net/detail/BIM-780619
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 1919
Record ID
BIM-780619