Effects of total flavonoids of raspberry on perimenopausal model in mice
Joint Authors
Miao, Mingsan
Fu, Zhenna
Wei, Zhenzhen
Source
Saudi Journal of Biological Sciences
Issue
Vol. 25, Issue 3 (31 Mar. 2018), pp.487-492, 6 p.
Publisher
Publication Date
2018-03-31
Country of Publication
Saudi Arabia
No. of Pages
6
Main Subjects
Topics
Abstract EN
To study the effect of raspberry total flavonoids on perimenopausal model in mice.
Blank group, sham operation, and the rest of the mice made the menopausal model.
Choose 72 mice castrated completely random divided into 6 groups for the experiment, respectively : model group, gengnianan (GNA) capsule group, soybean isoflavone soft (SIS) capsule group, high, mid and low dose group of total flavonoids of raspberry (TFR).
Animals in each group were given the corresponding drugs tenth days after operation, and were given intragastrical administration of once a day for continuous administration of 21 days.
Each group of mice in the administration of 18 days to determine the number of autonomic activities within 5 min, in the administration of 19–20 days to determine the incubation of the mice first entry into the darkroom and the number of shocks into the darkroom within 5 min.
At 2 h after the last administration (fasting for 12 h), mice were sacrificed and serum was collected.
Serum levels of E2, T, LH and FSH were measured.
Dissect the uterus, uterus, thymus and spleen.
Weigh the wet weight and calculate the organ index, the morphological changes of uterus, thymus and spleen were observed.
The results showed that the TFR had a good therapeutic effect on the perimenopausal model of mice after giving a high, mid and low dose of raspberry flavonoids for some time.
American Psychological Association (APA)
Fu, Zhenna& Wei, Zhenzhen& Miao, Mingsan. 2018. Effects of total flavonoids of raspberry on perimenopausal model in mice. Saudi Journal of Biological Sciences،Vol. 25, no. 3, pp.487-492.
https://search.emarefa.net/detail/BIM-780721
Modern Language Association (MLA)
Wei, Zhenzhen…[et al.]. Effects of total flavonoids of raspberry on perimenopausal model in mice. Saudi Journal of Biological Sciences Vol. 25, no. 3 (Mar. 2018), pp.487-492.
https://search.emarefa.net/detail/BIM-780721
American Medical Association (AMA)
Fu, Zhenna& Wei, Zhenzhen& Miao, Mingsan. Effects of total flavonoids of raspberry on perimenopausal model in mice. Saudi Journal of Biological Sciences. 2018. Vol. 25, no. 3, pp.487-492.
https://search.emarefa.net/detail/BIM-780721
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 492
Record ID
BIM-780721