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Morphologic and histopathologic changes associated with nandrolone decaonate (nandurabolin) on the seminal vesicle of rats
Other Title(s)
التغيرات المورفولوجية و النسيجية المصاحبة لعقار الناندرولين ديكونات على الحويصلة المنوية للفئران
Joint Authors
Dasuqi, Zaynab S.
Shakir, Abd al-Latif S.
Mubarak, Wafa A.
Ibrahim, Thabit Abd al-Munim
Afifi, Salah H.
Source
Assiut Veterinary Medical Journal
Issue
Vol. 63, Issue 153 (30 Apr. 2017), pp.166-171, 6 p.
Publisher
Assiut University Faculty of Veterinary Medicine
Publication Date
2017-04-30
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Natural & Life Sciences (Multidisciplinary)
Abstract EN
Twenty adult male rats three month old, weighing 80-190 gm were obtained from the Animal House Assiut University and divided into one control group and three treated groups (5 rats each group).
Treated groups were injected intramuscular with Nandrolene Decaonate at doses of 2.5,5, and 10mg/kg body weekly for three months.
At the end of exp.
the whole body weight and the seminal vesicle weight of both treated and control group were recorded.
The relation wight of the seminal vesicle to the body weight was increased significantly in treated group compared to the control.
The thickness of the smooth muscle fiber layer also was increased in treated groups compared to the control group.
Histopathologically, shortening of the mucosal folds, abundant seminal secretions, fragmentation of the smooth muscle fiber layer and hemorrhage and hyperemia below the muscular layer were observed.
Desquamation of the epithelium lining the folds of seminal vesicle was evident at a dose of 10mg/kg body weight of Nandrolene Decaonate.
The study concluded that Nandrolene Decaonate induced alterations in the seminal vesicle.
American Psychological Association (APA)
Dasuqi, Zaynab S.& Shakir, Abd al-Latif S.& Ibrahim, Thabit Abd al-Munim& Afifi, Salah H.& Mubarak, Wafa A.. 2017. Morphologic and histopathologic changes associated with nandrolone decaonate (nandurabolin) on the seminal vesicle of rats. Assiut Veterinary Medical Journal،Vol. 63, no. 153, pp.166-171.
https://search.emarefa.net/detail/BIM-780917
Modern Language Association (MLA)
Dasuqi, Zaynab S.…[et al.]. Morphologic and histopathologic changes associated with nandrolone decaonate (nandurabolin) on the seminal vesicle of rats. Assiut Veterinary Medical Journal Vol. 63, no. 153 (Apr. 2017), pp.166-171.
https://search.emarefa.net/detail/BIM-780917
American Medical Association (AMA)
Dasuqi, Zaynab S.& Shakir, Abd al-Latif S.& Ibrahim, Thabit Abd al-Munim& Afifi, Salah H.& Mubarak, Wafa A.. Morphologic and histopathologic changes associated with nandrolone decaonate (nandurabolin) on the seminal vesicle of rats. Assiut Veterinary Medical Journal. 2017. Vol. 63, no. 153, pp.166-171.
https://search.emarefa.net/detail/BIM-780917
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 170-171
Record ID
BIM-780917