BmNPV-miR-415 up-regulates the expression of TOR2 via Bmo-miR-5738
Joint Authors
Huang, Yong
Cao, Xueliang
Xia, Dingguo
Qiu, Zhiyong
Shen, Xingjia
Guo, Xijie
Zhao, Qiaoling
Source
Saudi Journal of Biological Sciences
Issue
Vol. 24, Issue 7 (30 Nov. 2017), pp.1614-1619, 6 p.
Publisher
Publication Date
2017-11-30
Country of Publication
Saudi Arabia
No. of Pages
6
Main Subjects
Topics
Abstract EN
MicroRNAs (miRNAs) have emerged as key players in host–pathogen interaction and many virus-encoded miRNAs have been identified (computationally and/or experimentally) in a variety of organisms.
A novel Bombyx mori nucleopolyhedrosis virus (BmNPV)-encoded miRNA miR-415 was previously identified through high-throughput sequencing.
In this study, a BmNPV-miR-415 expression vector was constructed and transfected into BmN cells.
The differentially expressed protein target of rapamycin isoform 2 (TOR2) was observed through two-dimensional gel electrophoresis and mass spectrometry.
Results showed that TOR2 is not directly a target gene of BmNPV-miR-415, but its expression is up-regulated by BmNPV-miR-415 via Bmo-miR-5738, which could be induced by BmNPV.
American Psychological Association (APA)
Cao, Xueliang& Huang, Yong& Xia, Dingguo& Qiu, Zhiyong& Shen, Xingjia& Guo, Xijie…[et al.]. 2017. BmNPV-miR-415 up-regulates the expression of TOR2 via Bmo-miR-5738. Saudi Journal of Biological Sciences،Vol. 24, no. 7, pp.1614-1619.
https://search.emarefa.net/detail/BIM-781602
Modern Language Association (MLA)
Cao, Xueliang…[et al.]. BmNPV-miR-415 up-regulates the expression of TOR2 via Bmo-miR-5738. Saudi Journal of Biological Sciences Vol. 24, no. 7 (Nov. 2017), pp.1614-1619.
https://search.emarefa.net/detail/BIM-781602
American Medical Association (AMA)
Cao, Xueliang& Huang, Yong& Xia, Dingguo& Qiu, Zhiyong& Shen, Xingjia& Guo, Xijie…[et al.]. BmNPV-miR-415 up-regulates the expression of TOR2 via Bmo-miR-5738. Saudi Journal of Biological Sciences. 2017. Vol. 24, no. 7, pp.1614-1619.
https://search.emarefa.net/detail/BIM-781602
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 1619
Record ID
BIM-781602