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Case of renal granulomatosis with polyangiitis following intravesical bacillus calmette-guérin therapy
Joint Authors
Silmi, Yusra
Khidr al-Faqih, Raniya
Jabali, Halah
Rais, Lamya
Zuaghi, Muhammad Karim
Krid, Madihah
Bin Fatimah, Layla
Beji, Sumayyah
Samawi, Wided
Source
Saudi Journal of Kidney Diseases and Transplantation
Issue
Vol. 29, Issue 1 (28 Feb. 2018), pp.185-188, 4 p.
Publisher
Saudi Center for Organ Transplantation
Publication Date
2018-02-28
Country of Publication
Saudi Arabia
No. of Pages
4
Main Subjects
Topics
Abstract EN
Various adverse reactions may occur after intravesical bacillus Calmette-Guérin (BCG) therapy.
Although the virulence of attenuated BCG is low, serious complications such as bacterial cystitis, bladder contractures, granulomatous prostatitis, epididymitis, orchitis, and systemic reactions such as fever and malaise have been described.
Disseminated granulomatosis such as hepatitis and pneumonitis have also been described, but are rare.
We report here the case of a 67-year-old patient who presented with renal granulomatosis with polyangiitis following intravesical BCG therapy for superficial bladder tumor.
The biological evaluation revealed the presence of perinuclear anti-neutrophil cytoplasmic antibodies with specificity for antimyeloperoxidase.
Renal biopsy specimen revealed pauci-immune crescentic glomerulonephritis with segmental glomerular necrosis, presence of granulomas and no evidence of any caseating necrosis.
He received antituberculosis drugs in addition to corticosteroids and cyclophosphamide without any improvement of the renal function
American Psychological Association (APA)
Silmi, Yusra& Khidr al-Faqih, Raniya& Jabali, Halah& Bin Fatimah, Layla& Samawi, Wided& Krid, Madihah…[et al.]. 2018. Case of renal granulomatosis with polyangiitis following intravesical bacillus calmette-guérin therapy. Saudi Journal of Kidney Diseases and Transplantation،Vol. 29, no. 1, pp.185-188.
https://search.emarefa.net/detail/BIM-781994
Modern Language Association (MLA)
Silmi, Yusra…[et al.]. Case of renal granulomatosis with polyangiitis following intravesical bacillus calmette-guérin therapy. Saudi Journal of Kidney Diseases and Transplantation Vol. 29, no. 1 (Jan. / Feb. 2018), pp.185-188.
https://search.emarefa.net/detail/BIM-781994
American Medical Association (AMA)
Silmi, Yusra& Khidr al-Faqih, Raniya& Jabali, Halah& Bin Fatimah, Layla& Samawi, Wided& Krid, Madihah…[et al.]. Case of renal granulomatosis with polyangiitis following intravesical bacillus calmette-guérin therapy. Saudi Journal of Kidney Diseases and Transplantation. 2018. Vol. 29, no. 1, pp.185-188.
https://search.emarefa.net/detail/BIM-781994
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 188
Record ID
BIM-781994