Tenofovir-induced Leukocytoclastic vasculitis

Joint Authors

al-Sulaymani, Abd al-Latif
Rasul, Wasif
al-Hamdani, Aishah
al-Busafi, Said A.

Source

Oman Medical Journal

Issue

Vol. 32, Issue 5 (30 Sep. 2017), pp.429-431, 3 p.

Publisher

Oman Medical Specialty Board

Publication Date

2017-09-30

Country of Publication

Oman

No. of Pages

3

Main Subjects

Medicine

Abstract EN

Tenofovir, a nucleotide analog, is one of the first-line medications recommended for the treatment of active chronic hepatitis B virus infection (CHB) and as a primary prophylaxis to prevent hepatitis B reactivation in cases of immunosuppression.

We report the first case of tenofovir-induced leukocytoclastic vasculitis (LCV).

A 43-year-old obese woman, who was known to have inactive CHB, was diagnosed with chronic immune thrombocytopenic purpura (ITP).

She was treated with corticosteroid therapy and was put on tenofovir to prevent hepatitis B virus reactivation.

A month later, she developed a skin rash, described as non-blanchable well-defined erythematous to violaceous papules and targetoid patches in her lower extremities.

A skin biopsy showed features of LCV.

The rash resolved completely within few days after replacing tenofovir with entecavir.

American Psychological Association (APA)

al-Busafi, Said A.& al-Sulaymani, Abd al-Latif& al-Hamdani, Aishah& Rasul, Wasif. 2017. Tenofovir-induced Leukocytoclastic vasculitis. Oman Medical Journal،Vol. 32, no. 5, pp.429-431.
https://search.emarefa.net/detail/BIM-784733

Modern Language Association (MLA)

al-Busafi, Said A.…[et al.]. Tenofovir-induced Leukocytoclastic vasculitis. Oman Medical Journal Vol. 32, no. 5 (Sep. 2017), pp.429-431.
https://search.emarefa.net/detail/BIM-784733

American Medical Association (AMA)

al-Busafi, Said A.& al-Sulaymani, Abd al-Latif& al-Hamdani, Aishah& Rasul, Wasif. Tenofovir-induced Leukocytoclastic vasculitis. Oman Medical Journal. 2017. Vol. 32, no. 5, pp.429-431.
https://search.emarefa.net/detail/BIM-784733

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references : p. 431

Record ID

BIM-784733