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Infection-related glomerulonephritis in a renal allograft
Joint Authors
Gopalakrishnan, Natarajan
Dineshkumar, Thanigachalam
Sakthirajan, Ramanathan
Balasubramaniyan, T.
Kurien, Anila Abraham
Abeesh, Padmanabha
Jeyachandran, Dhanapriya
Source
Saudi Journal of Kidney Diseases and Transplantation
Issue
Vol. 28, Issue 6 (31 Dec. 2017), pp.1421-1426, 6 p.
Publisher
Saudi Center for Organ Transplantation
Publication Date
2017-12-31
Country of Publication
Saudi Arabia
No. of Pages
6
Main Subjects
Topics
Abstract EN
Infection-related glomerulonephritis (IRGN) is an immune-mediated glomerulonephritis, most commonly caused by bacterial infections.
Although there is an increased incidence of infectious episodes in renal transplant recipients, IRGN as a cause of de novo glomerulonephritis is rarely seen probably due to impaired immunity.
We hereby report a 28-year-old male renal transplant recipient, who developed IRGN following impetigenous skin lesions after six years of transplant.
He developed rapid worsening of allograft function and was started on hemodialysis.
Allograft renal biopsy showed diffuse exudative endocapillary proliferation with crescents.
Electron microscopy revealed large subepithelial hump-like deposits.
Despite pulse steroid therapy, he became dialysis dependent.
Our patient is unique in the way that poststreptococcal glomerulonephritis in an adult after renal transplantation has not been reported so far.
We conclude that IRGN after renal transplant, though rare is a possible etiology for allograft dysfunction.
There is no definitive treatment protocol for this de novo glomerulonephritis which has an overall poor prognosis
American Psychological Association (APA)
Gopalakrishnan, Natarajan& Jeyachandran, Dhanapriya& Abeesh, Padmanabha& Dineshkumar, Thanigachalam& Kurien, Anila Abraham& Sakthirajan, Ramanathan…[et al.]. 2017. Infection-related glomerulonephritis in a renal allograft. Saudi Journal of Kidney Diseases and Transplantation،Vol. 28, no. 6, pp.1421-1426.
https://search.emarefa.net/detail/BIM-785698
Modern Language Association (MLA)
Gopalakrishnan, Natarajan…[et al.]. Infection-related glomerulonephritis in a renal allograft. Saudi Journal of Kidney Diseases and Transplantation Vol. 28, no. 6 (Nov. / Dec. 2017), pp.1421-1426.
https://search.emarefa.net/detail/BIM-785698
American Medical Association (AMA)
Gopalakrishnan, Natarajan& Jeyachandran, Dhanapriya& Abeesh, Padmanabha& Dineshkumar, Thanigachalam& Kurien, Anila Abraham& Sakthirajan, Ramanathan…[et al.]. Infection-related glomerulonephritis in a renal allograft. Saudi Journal of Kidney Diseases and Transplantation. 2017. Vol. 28, no. 6, pp.1421-1426.
https://search.emarefa.net/detail/BIM-785698
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 1425-1426
Record ID
BIM-785698