The endoglin (CD105)‎ expression as a marker of tumour vasculature in urinary bladder tumours of Iraqi patients

Joint Authors

Musa, Hind M.
Jasim, Aminah N.
Husayn, Mundhir J.

Source

Mesopotamia Environment Journal

Publisher

University of Babylon Environmental Research and Studies Center

Publication Date

2017-12-31

Country of Publication

Iraq

No. of Pages

6

Main Subjects

Natural & Life Sciences (Multidisciplinary)

English Abstract

process which mediates blood vessels formation.

The aim of this study to evaluate CD105 immunoexpressions in bladder tumors, and to determine its relation with clinico-pathological grades in patients with UBC .

The study included 50 biopsies from patients with urinary bladder carcinoma (UBC) and 15-benign bladder biopsies from patients with other bladder disorders rather than cancer (UBD).

CD105 immunostaining was assessed using Envision method .

Immunohistochemical (IHC) studying showed that (CD105) proteins were significantly high expressed in UBC compared with UBD patients (80 % vs.

33.3 % ; p≤ 0.01) , and there was significant difference in the positive IHC results of this protein in correlation to clinico-pathological grades in UBC patients (p ≤ 0.01).

we conclude that CD105 IHC expressionin bladder cancer may be consider as prognostic marker.

Data Type

Conference Papers

Record ID

BIM-787049

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